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Latest Telomerase Stories

2011-12-01 22:11:14

Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells´ sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research. Researchers would to like see their laboratory findings — published in the journal´s Dec. 5 print edition — lead to safer, more effective combination therapies for hard-to-treat pediatric brain cancers like medulloblastoma and high-grade...

2011-11-04 21:25:09

Scientists of the German Cancer Research Center have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes. The ends of the chromosomes, the telomeres, are repetitive DNA sequences that shorten every time a cell divides during the process of duplicating its genome. Once the telomeres become very short the cell stops dividing. Thus, telomeres work like a cellular clock that keeps an eye on the number of cell divisions. And once the...

2011-09-01 12:19:27

Study published in The American Journal of Pathology The first report of the presence of alternative lengthening of telomeres (ALT) in cancers arising from the bladder, cervix, endometrium, esophagus, gallbladder, liver, and lung was published today in The American Journal of Pathology. The presence of ALT in carcinomas can be used as a diagnostic marker and has implications for the development of anti-cancer drug therapies. Telomeres are nucleoprotein complexes located at the ends of...

2011-07-29 13:03:11

Telomeres, the complex structures that protect the end of chromosomes, of peripheral blood cells are significantly shorter in patients with familial breast cancer than in the general population. Results of the study carried out by the Human Genetics Group of the Spanish National Cancer Research Centre (CNIO), led by Javier Benitez, to be published in open-access journal PLoS Genetics on July 28th, reflect that familial, but not sporadic, breast cancer cases are characterized by shorter...

2011-07-21 16:15:00

HOUSTON, July 21, 2011 /PRNewswire/ -- America's #1 rated morning news program, The Today Show, featured a story highlighting SpectraCell's Telomere Test, a blood test that measures cellular aging. The segment entitled How to Live to 100 showcased SpectraCell's Telomere Test as a tool for those interested in monitoring their health with biomarkers specific to longevity and aging. The Telomere Test measures a person's biological age in comparison to their chronological age, giving a person...

2011-06-30 19:28:01

Scientists at Johns Hopkins have provided more clues to one of the least understood phenomena in some cancers: why the "ends caps" of cellular DNA, called telomeres, lengthen instead of shorten. In a study published online June 30 in Science Express, the Johns Hopkins researchers say they have identified two genes that, when defective, may cause these telomere elongations. Telomeres contain repeated sequences of DNA that, in normal cells, shorten each time a cell divides. Without telomeres,...

2011-06-21 12:39:41

Two Baylor College of Medicine doctors have received support for their research from Alex's Lemonade Stand, a nonprofit group dedicated to fighting pediatric cancer. Dr. Jason Shohet, assistant professor of pediatrics "“ hematology/oncology and co-chair of Texas Children's Cancer Center's Neuroblastoma Program, received a two-year, $200,000 Innovation Award from the organization for his research on reprogramming neuroblastoma cancer stem cells. Innovation Awards are given by Alex's...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'