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Latest Telomerase Stories

2011-06-08 08:00:00

NEW YORK, June 8, 2011 /PRNewswire/ -- When expressed (turned on), the gene (hTERT) located on Chromosome number 5p15.33 activates the enzyme telomerase. Human cells can keep living and dividing indefinitely when telomerase is continually present; i.e. the cells become immortal. Telomerase Activation Sciences, Inc. (T.A. Sciences®) announces TA-65® can extend human cell life indefinitely. TA-65® is a single molecule telomerase activator...

2011-05-23 14:22:03

A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres (protective caps on the ends of chromosomes), can be mimicked through the study of undifferentiated induced pluripotent stem cells, according to new findings from the Stanford University School of Medicine. Although dyskeratosis affects only about one in a million people, the scientists' findings could greatly facilitate research into this and other diseases caused by stem cell malfunctions,...

2011-05-06 14:25:04

Cancer researchers at UT Southwestern Medical Center are helping unlock the cellular-level function of the telomerase enzyme, which is linked to the disease's growth. Their latest findings, published today in Molecular Cell, demonstrate that telomerase repairs chromosomes in one of two ways "“ depending on whether a cell is dividing normally or if the cell is under stress from enzyme inhibition "“ and could lead to new or improved cancer-fighting therapies that promote inhibition...

2011-04-25 13:15:27

Adults with post-traumatic stress disorder and a history of childhood trauma had significantly shorter telomere length than those with PTSD but without childhood trauma, in a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco. Telomeres are DNA-protein complexes that cap the ends of chromosomes and protect them from damage and mutations. Short telomere length is associated with an increased risk of cancer, cardiovascular disease, and...

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2011-04-24 16:07:21

In stark contrast to normal cells, which only divide a finite number of times before they enter into a permanent state of growth arrest or simply die, cancer cells never cease to proliferate. Now, scientists at the Salk Institute for Biological Studies have uncovered an important clue to one of the mechanisms underlying cancer cell immortality.Their findings, published in the April 22, 2011 issue of Molecular Cell, reveal an unanticipated structure at chromosome ends, which could be a key...

2011-04-21 23:03:29

A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors. A report of the research led by University of North Carolina at Chapel Hill School of Medicine scientists was published in the April 22 online edition of the journal Science. The study focused on telomeres, a region of repetitive DNA sequence that protects the ends of chromosomes from deterioration or from fusing with other chromosomes. In many...

2011-04-19 12:51:24

Animals that reproduce asexually by somatic cloning have special mechanisms that delay ageing provide exceptionally good health. Scientists at the University of Gothenburg have shown how colony-forming ascidians (or sea squirts) can activate the enzyme telomerase, which protects DNA. This enzyme is more active also in humans who attain an advanced age. "Animals that clone themselves, in which part of an individual's body is passes on to the next generations, have particularly interesting...

2011-04-12 10:48:00

MALAGA, Spain, April 12, 2011 /PRNewswire/ -- Groundbreaking research touting the benefits of telomerase activation has been published in Aging Cell, the # 1 journal in geriatrics and gerontology. (Photo: http://photos.prnewswire.com/prnh/20100908/NY60832-a) (Logo: http://photos.prnewswire.com/prnh/20100908/NY60832LOGO-b ) The study, "The Telomerase Activator TA-65 elongates short telomeres and increases healthspan of adult/old mice without increasing cancer incidence" describes...

2011-04-04 19:49:47

UCSF scientists are reporting several studies showing that psychological stress leads to shorter telomeres "“ the protective caps on the ends of chromosomes that are a measure of cell age and, thus, health. The findings also suggest that exercise may prevent this damage. The team focused on three groups: post-menopausal women who were the primary caregivers for a family member with dementia; young to middle-aged adults with post-traumatic stress disorder; and healthy, non-smoking women...

2011-04-03 22:11:35

UT MD Anderson scientists also link the same SNP to longer telomeres A common genetic variation links to both bladder cancer risk and to the length of protective caps found on the ends of chromosomes, scientists at The University of Texas MD Anderson Cancer Center reported today at the AACR 102nd Annual Meeting. These endings or tips, called telomeres, guard against chromosomal damage and genomic instability that can lead to cancer and other diseases. "We found a single point of variation in...


Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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