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Latest Telomerase Stories

2011-04-25 13:15:27

Adults with post-traumatic stress disorder and a history of childhood trauma had significantly shorter telomere length than those with PTSD but without childhood trauma, in a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco. Telomeres are DNA-protein complexes that cap the ends of chromosomes and protect them from damage and mutations. Short telomere length is associated with an increased risk of cancer, cardiovascular disease, and...

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2011-04-24 16:07:21

In stark contrast to normal cells, which only divide a finite number of times before they enter into a permanent state of growth arrest or simply die, cancer cells never cease to proliferate. Now, scientists at the Salk Institute for Biological Studies have uncovered an important clue to one of the mechanisms underlying cancer cell immortality.Their findings, published in the April 22, 2011 issue of Molecular Cell, reveal an unanticipated structure at chromosome ends, which could be a key...

2011-04-21 23:03:29

A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors. A report of the research led by University of North Carolina at Chapel Hill School of Medicine scientists was published in the April 22 online edition of the journal Science. The study focused on telomeres, a region of repetitive DNA sequence that protects the ends of chromosomes from deterioration or from fusing with other chromosomes. In many...

2011-04-19 12:51:24

Animals that reproduce asexually by somatic cloning have special mechanisms that delay ageing provide exceptionally good health. Scientists at the University of Gothenburg have shown how colony-forming ascidians (or sea squirts) can activate the enzyme telomerase, which protects DNA. This enzyme is more active also in humans who attain an advanced age. "Animals that clone themselves, in which part of an individual's body is passes on to the next generations, have particularly interesting...

2011-04-12 10:48:00

MALAGA, Spain, April 12, 2011 /PRNewswire/ -- Groundbreaking research touting the benefits of telomerase activation has been published in Aging Cell, the # 1 journal in geriatrics and gerontology. (Photo: http://photos.prnewswire.com/prnh/20100908/NY60832-a) (Logo: http://photos.prnewswire.com/prnh/20100908/NY60832LOGO-b ) The study, "The Telomerase Activator TA-65 elongates short telomeres and increases healthspan of adult/old mice without increasing cancer incidence" describes...

2011-04-04 19:49:47

UCSF scientists are reporting several studies showing that psychological stress leads to shorter telomeres "“ the protective caps on the ends of chromosomes that are a measure of cell age and, thus, health. The findings also suggest that exercise may prevent this damage. The team focused on three groups: post-menopausal women who were the primary caregivers for a family member with dementia; young to middle-aged adults with post-traumatic stress disorder; and healthy, non-smoking women...

2011-04-03 22:11:35

UT MD Anderson scientists also link the same SNP to longer telomeres A common genetic variation links to both bladder cancer risk and to the length of protective caps found on the ends of chromosomes, scientists at The University of Texas MD Anderson Cancer Center reported today at the AACR 102nd Annual Meeting. These endings or tips, called telomeres, guard against chromosomal damage and genomic instability that can lead to cancer and other diseases. "We found a single point of variation in...

2011-04-03 21:42:47

Using new genetic information, scientists have linked a commonly found human genetic variant with both longer telomeres and reduced risk of bladder cancer, according to findings presented at the AACR 102nd Annual Meeting 2011, held April 2-6, and simultaneously published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Jian Gu, Ph.D., assistant professor of epidemiology at The University of Texas MD Anderson Cancer Center, said the single-nucleotide...

2011-03-31 08:26:00

MADRID, March 31, 2011 /PRNewswire/ -- Life Length the new biotechnology company that measures the length of telomeres, announced that Dr. Jerry W. Shay has been appointed as a Scientific Advisor. Stephen J. Matlin, CEO, Life Length said, "We are delighted to welcome Dr. Shay, one of the foremost world experts on aging and cancer to Life Length." Jerry W. Shay is Vice Chairman of the Department of Cell Biology at The University of Texas Southwestern Medical Center in Dallas,...

2011-03-24 18:01:44

New role for short telomeres New evidence has emerged from studies in mice that short telomeres or "caps" at the ends of chromosomes may predispose people to age-related diabetes, according to Johns Hopkins scientists. Telomeres are repetitive sequences of DNA that protect the ends of chromosomes, and they normally shorten with age, much like the caps that protect the end of shoelaces. As telomeres shorten, cells lose the ability to divide normally and eventually die. Telomere shortening has...