Quantcast

Latest Telomerase Stories

2011-06-17 03:00:00

BLUE BELL, Pa., June 17, 2011 /PRNewswire/ -- Inovio Pharmaceuticals, Inc. (NYSE Amex: INO) announced today that its subsidiary VGX Animal Health, Inc., a developer of DNA-based vaccines and therapies for companion and food animals, has achieved strong T cell responses from VAH-5000D, its DNA vaccine encoding telomerase reverse transcriptase (TERT) for the treatment of dogs with cancer. This preclinical data was presented by Dr. Douglas Kern, DVM, VGX Animal Health's Vice President of...

2011-06-16 07:18:12

(Ivanhoe Newswire) "“ Researchers have found new clues about aging, by identifying a new pathway that sets the clock for programmed aging in normal cells. The study focused on a toxic protein called progerin and its interaction with telomeres, which cap the ends of chromosomes. Telomeres wear away during cell division. When they degrade sufficiently, the cell stops dividing and dies. The researchers found that dysfunctional and short telomeres activate production of progerin, which is...

2011-06-13 16:03:15

Genetic splicing mechanism triggers both premature aging syndrome and normal cellular aging National Institutes of Health researchers have identified a new pathway that sets the clock for programmed aging in normal cells. The study provides insights about the interaction between a toxic protein called progerin and telomeres, which cap the ends of chromosomes like aglets, the plastic tips that bind the ends of shoelaces. The study by researchers from the National Human Genome Research...

2011-06-08 08:00:00

NEW YORK, June 8, 2011 /PRNewswire/ -- When expressed (turned on), the gene (hTERT) located on Chromosome number 5p15.33 activates the enzyme telomerase. Human cells can keep living and dividing indefinitely when telomerase is continually present; i.e. the cells become immortal. Telomerase Activation Sciences, Inc. (T.A. Sciences®) announces TA-65® can extend human cell life indefinitely. TA-65® is a single molecule telomerase activator...

2011-05-23 14:22:03

A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres (protective caps on the ends of chromosomes), can be mimicked through the study of undifferentiated induced pluripotent stem cells, according to new findings from the Stanford University School of Medicine. Although dyskeratosis affects only about one in a million people, the scientists' findings could greatly facilitate research into this and other diseases caused by stem cell malfunctions,...

2011-05-06 14:25:04

Cancer researchers at UT Southwestern Medical Center are helping unlock the cellular-level function of the telomerase enzyme, which is linked to the disease's growth. Their latest findings, published today in Molecular Cell, demonstrate that telomerase repairs chromosomes in one of two ways "“ depending on whether a cell is dividing normally or if the cell is under stress from enzyme inhibition "“ and could lead to new or improved cancer-fighting therapies that promote inhibition...

2011-04-25 13:15:27

Adults with post-traumatic stress disorder and a history of childhood trauma had significantly shorter telomere length than those with PTSD but without childhood trauma, in a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco. Telomeres are DNA-protein complexes that cap the ends of chromosomes and protect them from damage and mutations. Short telomere length is associated with an increased risk of cancer, cardiovascular disease, and...

20ba10d309542cfa9f09c88f36b43d701
2011-04-24 16:07:21

In stark contrast to normal cells, which only divide a finite number of times before they enter into a permanent state of growth arrest or simply die, cancer cells never cease to proliferate. Now, scientists at the Salk Institute for Biological Studies have uncovered an important clue to one of the mechanisms underlying cancer cell immortality.Their findings, published in the April 22, 2011 issue of Molecular Cell, reveal an unanticipated structure at chromosome ends, which could be a key...

2011-04-21 23:03:29

A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors. A report of the research led by University of North Carolina at Chapel Hill School of Medicine scientists was published in the April 22 online edition of the journal Science. The study focused on telomeres, a region of repetitive DNA sequence that protects the ends of chromosomes from deterioration or from fusing with other chromosomes. In many...

2011-04-19 12:51:24

Animals that reproduce asexually by somatic cloning have special mechanisms that delay ageing provide exceptionally good health. Scientists at the University of Gothenburg have shown how colony-forming ascidians (or sea squirts) can activate the enzyme telomerase, which protects DNA. This enzyme is more active also in humans who attain an advanced age. "Animals that clone themselves, in which part of an individual's body is passes on to the next generations, have particularly interesting...


Word of the Day
virgule
  • A punctuation mark (/) used to separate related items of information.
  • A little rod; a twig.
This word comes from the Late Latin 'virgula,' accentual mark, a diminutive of 'virga,' rod.
Related