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Latest Telomere Stories

2011-05-23 14:22:03

A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres (protective caps on the ends of chromosomes), can be mimicked through the study of undifferentiated induced pluripotent stem cells, according to new findings from the Stanford University School of Medicine. Although dyskeratosis affects only about one in a million people, the scientists' findings could greatly facilitate research into this and other diseases caused by stem cell malfunctions,...

2011-05-17 08:00:00

Study of institutionalized Romanian children finds prematurely shortened telomeres, a mark of cell aging BOSTON, May 17, 2011 /PRNewswire-USNewswire/ -- Studies in institutionalized Romanian children have found that the length of time spent in conditions of social deprivation and neglect correlates with lower IQ and behavioral problems. A new study, led by researchers at Children's Hospital Boston and Tulane University, shows that early adversity even affects children's chromosomes -...

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2011-05-16 14:43:53

A new blood test is going on sale this year that will predict how long someone has to live, based on their speed of aging. Researchers developed the $700 test that accurately measures the length of a person's telomeres, which is thought to be linked to longevity. Telomeres are sections of DNA that cap the ends of chromosomes, protecting them from damage and the loss of cell functions associated with aging. Life Length, a Spanish firm, developed the new commercial "death test," which it...

2011-05-06 14:25:04

Cancer researchers at UT Southwestern Medical Center are helping unlock the cellular-level function of the telomerase enzyme, which is linked to the disease's growth. Their latest findings, published today in Molecular Cell, demonstrate that telomerase repairs chromosomes in one of two ways "“ depending on whether a cell is dividing normally or if the cell is under stress from enzyme inhibition "“ and could lead to new or improved cancer-fighting therapies that promote inhibition...

2011-04-25 13:15:27

Adults with post-traumatic stress disorder and a history of childhood trauma had significantly shorter telomere length than those with PTSD but without childhood trauma, in a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco. Telomeres are DNA-protein complexes that cap the ends of chromosomes and protect them from damage and mutations. Short telomere length is associated with an increased risk of cancer, cardiovascular disease, and...

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2011-04-24 16:07:21

In stark contrast to normal cells, which only divide a finite number of times before they enter into a permanent state of growth arrest or simply die, cancer cells never cease to proliferate. Now, scientists at the Salk Institute for Biological Studies have uncovered an important clue to one of the mechanisms underlying cancer cell immortality.Their findings, published in the April 22, 2011 issue of Molecular Cell, reveal an unanticipated structure at chromosome ends, which could be a key...

2011-04-22 09:54:00

LA JOLLA, Calif., April 22, 2011 /PRNewswire-USNewswire/ -- After undergoing an extensive review process by Salk senior faculty, Non-Resident Fellows, and scientific leaders in their respective fields, Leanne Jones and Satchidananda Panda have been promoted to Associate Professor, and E.J. Chichilnisky, Andrew Dillin, Martin Hetzer, and Jan Karlseder to full Professor, the Salk Institute for Biological Studies announced today. "Faculty are the intellectual capital of the Salk Institute...

2011-04-21 23:03:29

A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors. A report of the research led by University of North Carolina at Chapel Hill School of Medicine scientists was published in the April 22 online edition of the journal Science. The study focused on telomeres, a region of repetitive DNA sequence that protects the ends of chromosomes from deterioration or from fusing with other chromosomes. In many...

2011-04-12 10:48:00

MALAGA, Spain, April 12, 2011 /PRNewswire/ -- Groundbreaking research touting the benefits of telomerase activation has been published in Aging Cell, the # 1 journal in geriatrics and gerontology. (Photo: http://photos.prnewswire.com/prnh/20100908/NY60832-a) (Logo: http://photos.prnewswire.com/prnh/20100908/NY60832LOGO-b ) The study, "The Telomerase Activator TA-65 elongates short telomeres and increases healthspan of adult/old mice without increasing cancer incidence" describes...

2011-04-04 19:49:47

UCSF scientists are reporting several studies showing that psychological stress leads to shorter telomeres "“ the protective caps on the ends of chromosomes that are a measure of cell age and, thus, health. The findings also suggest that exercise may prevent this damage. The team focused on three groups: post-menopausal women who were the primary caregivers for a family member with dementia; young to middle-aged adults with post-traumatic stress disorder; and healthy, non-smoking women...


Word of the Day
callithump
  • A somewhat riotous parade, accompanied with the blowing of tin horns, and other discordant noises; also, a burlesque serenade; a charivari.
'Callithump' is a back-formation of 'callithumpian,' a 'fanciful formation' according to the Oxford English Dictionary. However, the English Dialect Dictionary, says 'Gallithumpians' is a Dorset and Devon word from the 1790s that refers to 'a society of radical social reformers' or 'noisy disturbers of elections and meetings.'
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