Latest Telomere Stories
Researchers have revealed how a molecule called telomerase contributes to the control of the integrity of our genetic code, and when it is involved in the deregulation of the code, its important role in the development of cancer. The University of Montreal scientists involved explain how they were able to achieve their discovery by using cutting edge microscopy techniques to visualize telomerase molecules in real time in living cells in Molecular Cell on December 9, 2011. "Each time our...
Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells’ sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research. Researchers would to like see their laboratory findings – published in the journal’s Dec. 5 print edition – lead to safer, more effective combination therapies for hard-to-treat pediatric brain cancers like medulloblastoma and high-grade gliomas. To...
CINCINNATI, Dec. 1, 2011 /PRNewswire-USNewswire/ -- Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells' sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research. (Logo: http://photos.prnewswire.com/prnh/20110406/MM79025LOGO) Researchers would to like see their laboratory findings - published in the journal's Dec. 5 print edition - lead to safer, more effective...
A cell's genome maintains its integrity by organizing some of its regions into a super-compressed form of DNA called heterochromatin. In the comparatively simple organism fission yeast, a cellular phenomenon known as RNA interference (RNAi) plays an essential role in assembling heterochromatin, which keeps the compressed DNA in an inactive or "silent" state. Central to this process is a large protein complex that physically anchors various molecules involved in heterochromatin assembly to the...
Scientists of the German Cancer Research Center have discovered an alternative mechanism for the extension of the telomere repeat sequence by DNA repair enzymes. The ends of the chromosomes, the telomeres, are repetitive DNA sequences that shorten every time a cell divides during the process of duplicating its genome. Once the telomeres become very short the cell stops dividing. Thus, telomeres work like a cellular clock that keeps an eye on the number of cell divisions. And once the...
MIAMI, Oct. 10, 2011 /PRNewswire/ -- RevGenetics, a leading company in science based nutraceuticals, today announced that it will raise funding for new core research. "With the current brief rise in markets, we are also giving Wall street news that the nutraceutical business has an ace up its sleeve," said Anthony Loera, President of RevGenetics. "The nutraceutical and some cosmetic businesses have long been staples of good and stable performance even as markets go south. While many have...
Researchers have shown they can reverse the aging process for human adult stem cells, which are responsible for helping old or damaged tissues regenerate. The findings could lead to medical treatments that may repair a host of ailments that occur because of tissue damage as people age. A research group led by the Buck Institute for Research on Aging and the Georgia Institute of Technology conducted the study in cell culture, which appears in the September 1, 2011 edition of the journal...
Johns Hopkins researchers say data show aging alone, not hormonal impact of menopause, explains increasing number of deaths as women age Contradicting the long-held medical belief that the risk of cardiovascular death for women spikes sharply after menopause, new research from Johns Hopkins suggests instead that heart disease mortality rates in women progress at a constant rate as they age. The findings, published in BMJ, the British medical journal, could have implications for how...
Study published in The American Journal of Pathology The first report of the presence of alternative lengthening of telomeres (ALT) in cancers arising from the bladder, cervix, endometrium, esophagus, gallbladder, liver, and lung was published today in The American Journal of Pathology. The presence of ALT in carcinomas can be used as a diagnostic marker and has implications for the development of anti-cancer drug therapies. Telomeres are nucleoprotein complexes located at the ends of...
