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Latest Telomere Stories

2012-02-16 14:05:20

Every cell in the body has chromosomes with so-called telomeres, which are shortened over time and also through lifestyle choices such as smoking and obesity. Researchers have long speculated that the shortening of telomeres increases the risk of heart attack and early death. Now a large-scale population study in Denmark involving nearly 20,000 people shows that there is in fact a direct link, and has also given physicians a future way to test the actual cellular health of a person. In an...

2012-02-13 13:18:38

Researchers from the University of Geneva, Switzerland, discover how enzymatic onslaughts at the ends of our chromosomes are countered Researchers from the University of Geneva (UNIGE), Switzerland, have discovered the crucial role of two proteins in developing a cell 'anti-enzyme shield'. This protection system, which operates at the level of molecular 'caps' named telomeres, prevents cells from treating chromosome ends like accidental DNA breaks and 'repairing' them. Joining chromosome...

2012-01-19 13:50:35

Inherited mutation links exploding chromosomes to cancer An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University Hospital, all in Heidelberg, Germany, have discovered. Their study, published online today in Cell, also presents the first whole genome sequence...

2012-01-16 11:01:24

Telomeres, the very ends of chromosomes, become shorter as we age. When a cell divides it first duplicates its DNA and, because the DNA replication machinery fails to get all the way to the end, with each successive cell division a little bit more is missed. New research published in BioMed Central's open access journal Arthritis Research & Therapy shows that cells from osteoarthritic knees have abnormally shortened telomeres and that the percentage of cells with ultra short telomeres...

Longer Telomeres Mean Longer Lifespan
2012-01-11 05:57:06

A new study has found a possible predictor of lifespan. According to researchers at the University of Glasgow in England, the link lies in the telomeres that are located on an individual´s DNA. Telomeres are pieces of DNA that are located on the ends of chromosomal strands. They serve the same purpose as aglets on the ends of shoelaces, keeping the chromosome intact and preventing it from losing viable information over the course of a person´s lifetime. According to professor...

2011-12-08 23:34:46

Researchers have revealed how a molecule called telomerase contributes to the control of the integrity of our genetic code, and when it is involved in the deregulation of the code, its important role in the development of cancer. The University of Montreal scientists involved explain how they were able to achieve their discovery by using cutting edge microscopy techniques to visualize telomerase molecules in real time in living cells in Molecular Cell on December 9, 2011. "Each time our...

2011-12-01 22:11:14

Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells´ sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research. Researchers would to like see their laboratory findings — published in the journal´s Dec. 5 print edition — lead to safer, more effective combination therapies for hard-to-treat pediatric brain cancers like medulloblastoma and high-grade...

2011-11-14 11:32:32

A cell's genome maintains its integrity by organizing some of its regions into a super-compressed form of DNA called heterochromatin. In the comparatively simple organism fission yeast, a cellular phenomenon known as RNA interference (RNAi) plays an essential role in assembling heterochromatin, which keeps the compressed DNA in an inactive or "silent" state. Central to this process is a large protein complex that physically anchors various molecules involved in heterochromatin assembly to the...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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