Quantcast

Latest Temozolomide Stories

2009-08-04 07:52:00

VOORHEES, N.J., Aug. 4 /PRNewswire/ -- Treatment of glioblastoma (GBM), the most common type of glioma, presents many challenges. More than 50% of patients die of disease progression within 18 months of diagnosis. Current treatment includes the use of temozolomide-based chemotherapy, both concurrently with and after completion of radiotherapy. As healthcare professionals gain a better understanding of the molecular biology of GBM and utilize targeted therapies more frequently, there is hope...

2009-07-15 06:30:00

CALGARY, July 15 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced today that a poster presentation by Dr. Jacqueline Parker et al. entitled "Anti-Tumor Activity of Reovirus is Synergistically Enhanced in Combination with Temozolomide and Low Dose Irradiation in Primary Patient Glioma Xenografts Resistant to Treatment with Either Therapy Alone" was made yesterday at the 28th American Society for Virology (ASV) Annual Meeting. The meeting is being held in...

2009-07-02 08:00:00

EAST SETAUKET, N.Y., July 2 /PRNewswire-FirstCall/ -- Lixte Biotechnology Holdings (OTC Bulletin Board: LIXT) announced today that investigators of the National Institute of Neurological Disorders and Stroke (NINDS) and the National Cancer Institute (NCI), National Institutes of Health and Lixte reported that its novel compound, LB-1.2, enhances the effectiveness of two standard chemotherapy drugs in mouse models of human cancers. This research is being conducted under a Cooperative Research...

2009-03-10 14:22:59

The final results of a clinical trial show adding chemotherapy to radiotherapy treatment for brain tumors can extend a patient's survival for up to five years. Researchers focused their study on the most common and aggressive brain tumor, glioblastoma.  For over 30 years, post-operative radiotherapy was the standard treatment, but only offered modest survival benefits -- about nine months. In the clinical trial, scientists gave patients the chemotherapy drug temozolomide in combination...

2009-03-09 13:53:12

German and Swiss scientists say they have used the combination of two drugs to achieve a substantial improvement in the treatment of certain brain tumors. The researchers led by Professor Dr. Ulrich Herrlinger of the University of Bonn treated 39 patients who had been diagnosed with a gliablastoma. The patients -- treated with a combination of temozolomide and lomustine -- survived on average 23.1 months, while with the standard therapy the mean would have been 14.6 months, the researchers...

2009-03-09 07:00:00

A Drug That Improves Survival, When Added to Temodar/Temodal, Would Earn a 65 Percent Patient Share in the U.S. and a 30 Percent Patient Share in Europe in Newly Diagnosed Glioblastoma Multiforme, According to a New Report from Decision Resources WALTHAM, Mass., March 9 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed oncologists identify a therapy's effect on overall survival as the...

2009-03-05 07:00:00

Schering-Plough Receives EU and US Approvals for Intravenous Formulation of Temozolomide As Well As EU Approval for Oral Temozolomide Sachet Presentation KENILWORTH, N.J., March 5 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP) today announced that the European Commission and the US FDA both approved the intravenous (IV) formulation of temozolomide as an alternative to the already approved oral form of the drug. Temozolomide is marketed as TEMODAL(R) in the EU and as...

2009-02-17 06:00:00

TSX: BMR TORONTO, Feb. 17 /PRNewswire-FirstCall/ - Bradmer Pharmaceuticals Inc. (BMR.TSX), provided an update today on the ongoing Phase III GLASS-ART Trial testing Neuradiab(R) in the most advanced form of brain cancer (glioblastoma). Bradmer also announced that its Board of Directors has recommended a review of strategic options in light of performance, market conditions and new projections of site initiation and patient enrollment from the Company's clinical research organization (CRO)....

2009-01-19 07:00:00

Ipilimumab Will Earn Decision Resources' Clinical Gold Standard for Stage IV Malignant Melanoma in 2012, According to a New Report from Decision Resources WALTHAM, Mass., Jan. 19 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that a drug for treating stage IV malignant melanoma that can increase median overall survival when compared with standard of care dacarbazine (Bedford Laboratories' DTIC-Dome,...

2008-12-18 15:30:00

NEEDHAM, Mass. and NEW YORK, Dec. 18 /PRNewswire-FirstCall/ -- Celldex Therapeutics (Nasdaq: CLDX) and Pfizer Inc. (NYSE: PFE) today announced plans to amend the ongoing ACT III clinical trial involving the investigational compound, CDX-110. ACT III is a randomized open-label, two-arm, Phase 2b/3 trial comparing CDX-110 combined with temozolomide to temozolomide alone in patients with newly diagnosed Glioblastoma Multiforme (GBM). Only the Phase 2b portion of the trial has been open to...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'