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Latest Tetraploid complementation assay Stories

Moving Forward In Stem Cell Research By Rewinding Development
2013-06-07 08:14:01

University of Copenhagen Scientists at the Danish Stem Cell Center, DanStem, at the University of Copenhagen have discovered that they can make embryonic stem cells regress to a stage of development where they are able to make placenta cells as well as the other fetal cells. This significant discovery, published in the journal Cell Reports today, has the potential to shed new light on placenta related disorders that can lead to problematic pregnancies and miscarriages. Embryonic stem...

Stem Cells Produced From Peripheral Blood Through Novel Technique
2012-11-01 12:56:14

Jove (Journal of Visualized Experiments) Stem cells are a valuable resource for medical and biological research, but are difficult to study due to ethical and societal barriers. However, genetically manipulated cells from adults may provide a path to study stem cells that avoid any ethical concerns. A new video-protocol in JoVE (Journal of Visualized Experiments), details steps to generate human induced pluripotent stem cells (iPSC) from cells in the peripheral blood.  The technique...

2012-03-02 13:06:04

FINDINGS: Devising a novel method to identify potential genetic regulators in planarian stem cells, Whitehead Institute scientists have determined which of those genes affect the two main functions of stem cells. Three of the genes are particularly intriguing because they code for proteins similar to those known to regulate mammalian embryonic stem cells. Such genetic similarity makes planarians an even more attractive model for studying stem cell biology in vivo. RELEVANCE: Stem cells may...

Scientists Create Mammalian Cells With Single Chromosome Set
2011-09-08 06:14:18

  Researchers have created mammalian cells containing a single set of chromosomes for the first time in research funded by the Wellcome Trust and EMBO. The technique should allow scientists to better establish the relationships between genes and their function. Mammal cells usually contain two sets of chromosomes — one set inherited from the mother, one from the father. The genetic information contained in these chromosome sets helps determine how our bodies develop. Changes...

2011-08-17 13:20:43

Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue. The researchers, from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, found that the progeny of the human embryonic stem cells and induced...

2011-03-07 14:24:45

The diagnostic test enables accurate, rapid assessment of the quality of stem cell lines "Pluripotent" stem cells"”which have the potential to mature into almost any cell in the body"”are being widely studied for their role in treating a vast array of human diseases and for generating cells and tissues for transplantation. Now, a team of Scripps Research Institute scientists has created a quality control diagnostic test that will make it much easier for researchers to determine...

2010-04-25 15:19:47

Better understanding of mechanisms involved should improve reprogramming of embryonic-like cells Scientists may be one step closer to being able to generate any type of cells and tissues from a patient's own cells. In a study that will appear in the journal Nature and is receiving early online release, investigators from the Massachusetts General Hospital Center for Regenerative Medicine (MGH-CRM) and the Harvard Stem Cell Institute (HSCI), describe finding that an important cluster of genes...

2010-02-15 14:20:56

The great promise of induced pluripotent stem cells is that the all-purpose cells seem capable of performing all the same tricks as embryonic stem cells, but without the controversy. However, a new study published this week (Feb. 15) in the Proceedings of the National Academy of Sciences comparing the ability of induced cells and embryonic cells to morph into the cells of the brain has found that induced cells "” even those free of the genetic factors used to program their all-purpose...

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2009-07-24 06:35:00

Scientists on Thursday announced the creation of mice from reprogrammed induced pluripotent stem cells. Writing in the journal Nature, Dr. Shaorong Gao and colleagues from the National Institute of Biological Sciences in Beijing, China said they used a new technique to make Xiao Xiao, or Tiny, as the first mouse ever created from reprogrammed adult pluripotent cells. "This gives us hope for future therapeutic interventions," said Fanyi Zeng of the Shanghai Institute of Medical Genetic at...

2009-07-23 11:36:17

In a paper publishing online July 23 in Cell Stem Cell, a Cell Press journal, Dr. Shaorong Gao and colleagues from the National Institute of Biological Sciences in Beijing, China, report an important advance in the characterization of reprogrammed induced pluripotent stem cells, or iPSCs.Scientists working with iPSCs have been eager to find out if these cells are fully pluripotent, as this would tell us to what extent they have in fact been truly reprogrammed and resemble normal embryonic...


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