Latest TGF beta Stories
Many mechanisms change the activity of genes.
Ovarian cancer is the leading cause of death among gynecological cancers.
There are many mechanisms that alter the activity of genes â€“ direct changes to the DNA code like mutations and deletions, or changes that control when genes are switched on and off, called epigenetic means.
St. Jude Children's Research Hospital scientists have identified a new pathway that helps control the immune balance through reciprocal regulation of specialized T ymphocytes, which play very different inflammatory roles.
Oncogenes are like friends who've gone off the deep end.
Several years ago, Dr. Arthur Beaudet, Baylor College of Medicine's chair of molecular and human genetics, was surprised to find that mice that lacked a protein called E-selectin ligand-1 were shorter than normal.
Animal study suggests new target that might help aid recovery for patients with traumatic injuries.
By examining tissue removed during breast reduction surgery in healthy women, researchers at Georgetown Lombardi Comprehensive Center have found a molecule they say identified women who had atypical hyperplasia, a potentially precancerous condition in which cells are abnormally increased.
The spread, or metastasis, of individual breast cancer cells from the main tumor into the blood circulation to the lungs and other body tissues and organs is under the control of a growth factor abbreviated TGFb.
UT Southwestern Medical Center researchers have found that a naturally occurring protein â€” transforming growth factor beta1 (TGF-ÃŸ1) â€” which normally suppresses the growth of cancer cells, causes a rebound effect after a prolonged exposure.