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Last updated on April 23, 2014 at 1:22 EDT

Latest The Hallmarks of Cancer Stories

2013-05-21 16:27:44

Study clarifies roles of anti-angiogenic proteins in discouraging metastasis and reveals potential anti-metastasis drug BOSTON, May 21, 2013 /PRNewswire-USNewswire/ -- By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer. The findings suggest that...

2013-02-26 14:39:33

Researchers at the University of Hawai'i Cancer Center have uncovered a novel mechanism that may lead to more selective ways to stop cancer cells from spreading. Associate Professor Joe W. Ramos PhD, a cancer biologist at the UH Cancer Center and his team have identified the role of the protein RSK2 in cancer cell migration, part of the process of cancer metastasis. Cancer becomes metastatic when cells break away from the primary tumor and spread to other parts of the body. Metastatic...

2013-02-19 12:20:51

A Basque research consortium has managed to halt the progress of colon cancer and its metastasis in the liver in an experimental model with mice. This advance, that may open a new path for the future treatment of such pathologies, has been achieved by creating molecules which interfere with the adhesion of tumor cells to other cells of the organism. In this way, the molecules halt both the growth of the tumor and the dissemination of the tumor to and its proliferation in other organs. The...

Cancer Cells Break Away
2012-10-11 09:30:45

Connie K. Ho for redOrbit.com — Your Universe Online A new study from the Massachusetts Institute of Technology (MIT) has revealed that cancer cells break away from tumors via adhesion molecules, causing a spread of cancer throughout the body. The findings from the research project were recently published in the journal Nature Communications and offer a glimpse into the possible development of cancer drug targets. “As cancer cells become more metastatic, there can be a...