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Latest The New England Journal Stories

2009-11-25 16:00:00

SILVER SPRING, Md., Nov. 25 /PRNewswire-USNewswire/ -- An article by Janet Woodcock, M.D., director of the FDA's Center for Drug Evaluation and Research, titled "A Difficult Balance - Pain Management, Drug Safety, and the FDA," appears in the Nov. 26, 2009 issue of The New England Journal of Medicine. (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO) In the article, Woodcock discusses FDA efforts to strike a balance between access to pain medication for those who need it and...

2009-10-20 03:50:00

PARIS, Oct. 20 /PRNewswire-USNewswire/ -- Detailed results from the Prime-Boost HIV Vaccine Clinical Trial involving more than 16,000 adult volunteers in Thailand show that an investigational HIV vaccine regimen was safe and modestly effective at reducing the rate of HIV infection compared to placebo. These results were presented today by the trial collaborators to researchers gathered at the AIDS Vaccine 2009 Conference in Paris, France and published online by The New England Journal of...

2009-09-24 07:24:15

Following one of the largest studies ever conducted in Parkinson's disease (PD), researchers at Mount Sinai School of Medicine report today in The New England Journal of Medicine that rasagiline, a drug currently used to treat the symptoms of PD, may also slow the rate of disease progression. Known as ADAGIO (Attenuation of Disease Progression with Azilect Given Once Daily), the 18-month study used a novel design called the delayed start. In this type of study, patients are randomized to...

2009-09-10 08:18:13

The source of PML, the JC virus, is found to be reactivated in multiple sclerosis patients receiving natalizumab treatment The virus responsible for PML (progressive multifocal leukoencephalopathy), a rare brain disease that typically affects AIDS patients and other individuals with compromised immune systems, has been found to be reactivated in multiple-sclerosis patients being treated with natalizumab (Tysabri). The findings, led by scientists at Beth Israel Deaconess Medical Center...

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2009-08-28 10:20:00

Increased use of medical scans could have a dangerous impact on the health of Americans under age 65, according to a recent study. Writing in The New England Journal Of Medicine, Dr. Reza Fazel of Emory University and colleagues, found that the cumulative amount of radiation from repeated scans could pose a health risk to patients. Fazel and his team conducted a three-year study of almost 1 million Americans between the ages of 18 and 64. The study was based on data from a 2005-2007 survey of...

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2009-05-27 06:10:00

The new chiefs of the Food and Drug Administration stated that the recent salmonella outbreak from peanut butter was representative of a failure by the agency - one they are focused on repairing.  The outbreak resulted in over 700 cases nationwide and at least nine deaths. According to the Associated Press, the FDA is widely viewed as an agency floundering amidst increasing responsibilities, insufficient budgets and staffing and overseeing the nation's complex healthcare...

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2009-01-27 15:11:30

The afflictions of impoverished Cambodia can be seen in the nation's western corner:  girls for hire standing outside restaurants, uneven dirt roads dotted with signs that warn "Danger Mines!" But a potentially greater danger lurks there, particularly for the outside world. The parasite that causes the most lethal form of malaria is showing initial signs of resistance to the best new drug that treats the disease, the New York Times reports. Combination treatments using the antimalaria...

2009-01-02 15:13:10

A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan. 1, 2009 issue of The New England Journal of Medicine, were made by an international team of scientists, composed of 14 researchers from the...

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2008-09-11 09:05:00

By Gina Kolata New York Times News Service A study has found that surgery is no better than more conservative treatment to relieve knee pain caused by arthritis. In the study, being published Thursday in The New England Journal of Medicine, 86 patients who had the operation fared no better over two years than 86 who had physical therapy and took medications to dampen inflammation. The results of the study are in line with those from a study published in 2002. But experts are divided about...

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2008-01-31 10:20:00

Iowa Senator Charles Grassley said yesterday that Dr. Steven M. Haffner, a well-known diabetes expert at the University of Health Science Center in San Antonio, had leaked confidential, unpublished information to GlaxoSmithKline (GSK) that questioned the safety of the company's diabetes drug Avandia.A New York Times report said that Dr. Haffner had faxed the document, a medical journal article he had agreed to read as part of the normal prepublication peer review process for The New England...