Latest Thiazide Stories
Discovery may help prevent kidney damage in organ transplant patients Modern medicine’s ability to save lives through organ transplantation has been revolutionized by the development of drugs that prevent the human body from rejecting the transplanted organ. But those antirejection drugs have their own side effects — sometimes serious. A group of researchers led by scientists at Oregon Health & Science University have discovered the process that may be causing many of those...
In a review of earlier studies, researchers at National Heart, Lung, and Blood Institute (NHLBI) found that the drug, a diuretic, or "water pill," called hydrochlorothiazide, lowered blood pressure by only about half as much as common alternatives such as beta blockers and ACE inhibitors. This would make the world's most popular blood pressure medicine much less effective than comparable drugs and give patients a false sense of security, the researchers said Monday to Reuters Health.The drug...
Academic detailing"”a method involving face-to-face education of clinicians by investigators trained to present trial findings and guidelines"”may have been associated with a small change in prescribing patterns for patients with high blood pressure, according to a report in the May 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals."Ensuring that important clinical trial findings are reflected in the practices of community physicians remains a substantial...
Using beta-blockers as a second-line therapy in combination with certain anti-hypertensive drugs significantly lowers blood pressure in patients with hypertension, according to a systematic review by Cochrane Researchers. This review also goes some way to explaining the differences in the way that patients respond to beta-blockers and other classes of blood pressure lowering drugs.Beta-blockers are commonly used in the treatment of hypertension (high blood pressure) to help reduce the risk of...
Researchers at the University of Maryland School of Medicine have made an important discovery about why potassium builds up to dangerous levels in the bloodstream, a relatively common medical problem that affects about eight percent of hospitalized patients. They have identified a new molecular pathway and a new class of molecules responsible for preventing potassium from being excreted normally through the kidney. Their study was just published in the Journal of Clinical Investigation.The...
NEW YORK (Reuters Health) - Diuretics and beta-blockers, used to treat hypertension, are associated with an increased risk of developing type 2 diabetes, new findings indicate."The relation between the use of different classes of antihypertensive medications and the risk of incident type 2 diabetes is unclear," Dr. Eric N. Taylor, of Harvard Medical School, Boston, and colleagues write in the medical journal Diabetes Care. "Prior studies have reported conflicting...
