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Latest Thoracic aortic aneurysm Stories

2013-03-11 10:31:26

The belief among medical professionals in the 1950s that the mortality rate for type A acute aortic dissection during the initial 24 hours was one to two percent per hour appears to hold true in the contemporary era of treatment, based on a review of the large-scale IRAD registry being presented March 9 at the American College of Cardiology (ACC) Scientific Sessions. "In the 1950s, the medical literature suggested that the mortality rate for type A acute aortic dissection was one percent...

2012-09-06 13:58:03

Endovascular repair has low rate of complications, even in high-risk patients A minimally invasive procedure known as endovascular repair used for abdominal aortic aneurysms has a low rate of complications, even in high-risk patients such as those with kidney, heart or lung problems, a Mayo Clinic study shows. Researchers found that even when aneurysms ruptured, endovascular repair had lower mortality rates than open-abdominal surgery, the other treatment option. The findings are being...

2012-07-09 16:28:35

Systemic complications include life-threatening thoracic aortic disease Research teams from The University of Texas Health Science Center at Houston (UTHealth) and Paris, France have discovered a gene defect linked to a cluster of systemic complications, including life-threatening thoracic aortic disease and intracranial aneurysms. The new syndrome is similar, but distinct from known syndromes such as Marfan and Loeys-Dietz syndrome. Genome-wide analysis of two unrelated families, one...

2012-02-09 18:28:10

Some doctors might see a patient with Marfan syndrome once or twice a year. But Dr. Joseph Coselli, professor of surgery at Baylor College of Medicine and chief of adult cardiac surgery at the Texas Heart Institute, sees on average one or more a week. While Marfan syndrome is a disease of the connective tissue and can affect many areas on the body, it can become deadly when it affects the heart or aorta. What is Marfan syndrome? Marfan syndrome is caused by a defect in a gene that...

2011-11-11 06:50:52

(Ivanhoe Newswire) -- Medical scientists have for the first time identified a gene responsible for a fatal abdominal condition that afflicts tens of thousands of people across the world. An international team led by Matt Bown, a vascular surgeon from the University of Leicester, identified a single gene that is linked to the development of abdominal aortic aneurysms, AAAs. What is more, the team discovered that the gene, LRP1, was not linked to other cardiovascular diseases, suggesting...

2011-09-13 23:10:03

While the incidence of the life-threatening condition of aortic dissection is significantly higher than in the general population, it remains low among patients with the congenital heart defect, bicuspid aortic valve; however, the incidence of aortic aneurysms is significantly high, according to a study in the September 14 issue of JAMA. Bicuspid aortic valve (BAV; defect of the aortic valve that results in the formation of two flaps that open and close, instead of the normal three) is the...

2011-09-12 12:09:44

Multi-institutional study reveals risk factor that doubles chance of developing silent killer Richard Holbrooke, John Ritter, Lucille Ball, Jonathan Larson and Great Britain's King George II were all taken by the same silent killer: an acute aortic dissection. Now, scientists led by researchers at The University of Texas Health Science Center at Houston (UTHealth) and Baylor College of Medicine (BCM) have found an association with a common genetic variant in the population that...

2011-06-17 13:20:01

Results published today in PLoS Genetics Patients with thoracic aortic aneurysms that lead to acute aortic dissections are 12 times more likely to have duplications in the DNA in a region of chromosome 16 (16p13.1) than those without the disease, according to a study led by genetic researchers at The University of Texas Health Science Center at Houston (UTHealth). The results of the innovative study, which included researchers at Baylor College of Medicine, are published in the June 16 issue...

2011-06-17 13:09:38

People who have duplications in a region of chromosome 16 (16p13.1) that is present in approximately 1 in 1000 individuals have a 12-fold increased risk of thoracic aortic aneurysms leading to a tear in the aorta, or acute aortic dissections. An estimated 10000 people die annually from thoracic aortic aneurysms and dissections (TAAD) in the United States, where TAAD have ranked as high as the 15th leading cause of death. The study, led by genetic researchers at The University of Texas Health...

2010-11-18 16:26:58

Researchers find fifth gene defect, 47 DNA regions linked to disease Discovery of a fifth gene defect and the identification of 47 DNA regions linked to thoracic aortic disease are the subject of studies released this month involving researchers at The University of Texas Health Science Center at Houston (UTHealth). In both studies, the investigators have identified alterations in the genetic material or DNA that affect the ability of smooth muscle cells, which line the aorta and other blood...


Latest Thoracic aortic aneurysm Reference Libraries

Marfan's Syndrome
2013-07-19 15:22:33

Marfan's syndrome is a genetic disorder of the connective tissue that causes excessively tall stature and long extremities. It is carried by the gene FBN1, which encodes the connective protein fibrillin-1, and is a dominant trait. The human genetic makeup contains a pair of FBN1 genes, so because of its dominance, inheriting one affected FBN1 gene from either parent will result in Marfan's syndrome. It effects both males and females, and has no ethnic bias. It was named after Antoine Marfan,...

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Word of the Day
barghest
  • A goblin in English folklore, often appearing in the shape of a large dog and believed to portend imminent death or misfortune.
  • A ghost, wraith, hobgoblin, elf, or spirit.
The origin of 'barghest' is not known, but it may be from perhaps burh-ghest, town-ghost, or German Berg-geist (mountain spirit) or Bär-geist (bear-spirit).
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