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Latest Thymidine kinase Stories

2011-08-16 12:39:19

A clinical trial has shown that a form of gene therapy is safe for treating a deadly form of brain cancer, even when combined with radiation therapy. The phase 1b trial was conducted at the Ohio State University Comprehensive Cancer Center "“ Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC "“ James) and at Methodist at Hospital in Houston, TX. The novel treatment uses an adenovirus vector called AdV-tk. The vector is taken up by cancer cells where...

2010-05-13 08:00:00

SAN FRANCISCO, May 13 /PRNewswire/ -- Jennerex, Inc., a clinical-stage cancer biotherapeutics company, today announced that key data from its JX-594 intravenous administration Phase 1 dose escalation clinical study will be presented at the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting taking place May 19-22, 2010, in Washington DC. The presentation details are as follows: Abstract #33: "Demonstration of Delivery and Antitumoral Activity of JX-594, a Targeted...

2009-04-28 12:32:32

Some DNA repair enzymes can become double-edged swords "“ If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used cancer drug 5-Fluorouracil (5FU) and help clinicians to predict patient's response to chemotherapy, according to new findings from the University of Basel, Switzerland. The work, published in this week's issue of PLoS Biology, reports that 5FU keeps the DNA-repair...

2009-01-12 19:00:00

U.S. researchers say they used the human genetic code to attract key immune cells into the brain, where they then recognized and attacked tumor cells. The Cedars-Sinai Medical Center researchers in Los Angeles discovered that a protein known as high-mobility group box 1, or HMGB1, released from dying tumor cells activates key immune cells called dendritic cells and stimulates a strong and effective anti-tumor immune response. But the number of dendritic cells in the brain is very small,...

2008-06-25 03:02:02

By Tumeh, Paul C Radu, Caius G; Ribas, Antoni Immune system activation can be elicited in viral infections, active immunization, or cancer immunotherapy, leading to the final common phenotype of increased glycolytic use by immune cells and subsequent detection by ^sup 18^F-FDG PET. Because ^sup 18^F-FDG is also used in baseline staging PET/CT scans and in tumor response assessment, physicians are faced with a unique challenge when evaluating tumor response in patients receiving cancer...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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