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Latest Tissue plasminogen activator Stories

2012-07-18 10:30:50

Even when its clot-dissolving powers are removed, the stroke drug tPA can still protect brain cells from the loss of oxygen and glucose induced by a stroke, researchers have discovered. The finding suggests that a modified version of tPA could provide benefits to patients who have experienced a stroke, without increasing the risk of bleeding. The results will be published in the Journal of Neuroscience. "We may have been giving the right medication, for the wrong reason," says senior...

2012-06-27 10:35:00

The clot-busting medicine, tPA (tissue plasminogen activator), is safe to use in acute stroke patients already on the home blood thinner warfarin, according to researchers from Duke Clinical Research Institute (DCRI). This study helps allay previous concerns that tPA was too dangerous to use in patients on home anticoagulation and would lead to high risk for potentially fatal intracranial bleeding. "To date, we have no randomized trials or large cohort studies to guide us," says Ying Xian,...

2012-06-27 06:32:12

(Ivanhoe Newswire) — Researchers from the Duke Clinical Research Institute have ruled the clot-busting drug tPA (tissue plasminogen activator) safe for acute stroke patients on the home blood thinner warfarin. The drug was previously thought to be too dangerous to use in patients on home anticoagulation for fear of a higher risk of fatal intracranial bleeding. "To date, we have no randomized trials or large cohort studies to guide us," Ying Xian, M.D., Ph.D., assistant professor of...

2012-06-11 19:05:16

Findings show new therapy has potential to help the brain as it reacts to stroke's harmful effects Researchers at the University of Missouri have demonstrated the effectiveness of a potential new therapy for stroke patients in an article published in the journal Molecular Neurodegeneration. Created to target a specific enzyme known to affect important brain functions, the new compound being studied at MU is designed to stop the spread of brain bleeds and protect brain cells from further...

2012-05-11 11:59:39

American Heart Association meeting report - Abstract 10 Acute ischemic stroke patients taking the blood thinner warfarin can be treated safely with the clot-busting drug tissue plasminogen activator (tPA), according to research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2012. "Although it's the only drug approved by the Food and Drug Administration to treat acute ischemic stroke, tPA is underused among patients on home...

2012-05-03 15:59:49

UD researchers discover that JAM-A protein keeps blood clots in check Cut your toe, and platelets -- those disc-shaped cells circulating in your blood  -- rush to the scene, clumping together to plug the leak. But when an unwanted clot forms in an artery, and an overaccumulation of platelets blocks blood flow, a heart attack or stroke occurs, too often with fatal results. Heart disease and stroke rank as humankind´s top killers, according to the World Health Organization....

2012-05-02 15:13:46

The mantra in stroke care is “time is brain.” With each passing minute more brain cells are irretrievably lost and, because of this, timely diagnosis and treatment is essential to increase the chances for recovery. While significant strides have been made to improve the response time of caregivers, a new study shows that a critical step in the process — imaging of the brain to determine the nature of the stroke — is still occurring too slowly at too many hospitals....

2012-03-28 00:35:25

Study finds new treatment approach could benefit hundreds of thousands per year Pulmonary embolism -- the sudden blockage of an artery in the lung -- is estimated to cause over 100,000 deaths each year in the U.S. Although thrombolytics, or "clot-buster" drugs, are currently reserved to treat only the most severe cases of pulmonary embolism, new data suggest that when used at lower doses, these drugs are also safe and effective for more common, moderate cases of pulmonary embolism,...

2012-03-27 05:16:31

(Ivanhoe Newswire)-- There is only one stroke treatment option available today and with such a high rate of individuals suffering from strokes, many would agree that a new solution is necessary. Now researchers from Stanford University have shown that by removing a matching set of molecules responsible for assisting in regulation of the brain's capacity for forming and breaking connections between nerve cells could greatly increase recovery from a stroke just days after occurring....


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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