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Latest Tissue plasminogen activator Stories

2012-03-28 00:35:25

Study finds new treatment approach could benefit hundreds of thousands per year Pulmonary embolism -- the sudden blockage of an artery in the lung -- is estimated to cause over 100,000 deaths each year in the U.S. Although thrombolytics, or "clot-buster" drugs, are currently reserved to treat only the most severe cases of pulmonary embolism, new data suggest that when used at lower doses, these drugs are also safe and effective for more common, moderate cases of pulmonary embolism,...

2012-03-27 05:16:31

(Ivanhoe Newswire)-- There is only one stroke treatment option available today and with such a high rate of individuals suffering from strokes, many would agree that a new solution is necessary. Now researchers from Stanford University have shown that by removing a matching set of molecules responsible for assisting in regulation of the brain's capacity for forming and breaking connections between nerve cells could greatly increase recovery from a stroke just days after occurring....

2012-03-09 00:56:00

Everyone is familiar with the pain of skinned knees. However, the complex pathway of proteins that works behind the scenes after the bleeding has stopped is not as well known. Central to this process is the production of plasmin, a powerful blood enzyme that disposes of blot clots. Doctors also harness the "clot busting" abilities of plasmin to treat patients who suffer heart attack or stroke. Now, a study published by Cell Press on March 8th in the journal Cell Reports provides remarkable...

2012-03-07 11:18:05

Thromboembolic stroke, caused by a blood clot in the brain, results in damage to the parts of the brain starved of oxygen. Breaking up the clot with tissue plasminogen activator (tPA) reduces the amount of damage, however, there is a very short time window when the value of the treatment outweighs the side effects. New research published in BioMed Central's open access journal Experimental & Translational Stroke Medicine shows that, during the first 24 hours after a stroke, mild...

2012-02-03 19:00:24

An experimental device for removing blood clots in stroke patients dramatically outperformed the standard mechanical treatment, according to research presented by UCLA Stroke Center director Dr. Jeffrey L. Saver at the American Stroke Association's 2012 international conference in New Orleans on Feb. 3. The SOLITAIRE Flow Restoration Device is among an entirely new generation of devices designed to remove blood clots from blocked brain arteries in patients experiencing stroke. It has a...

2012-02-03 19:00:55

CT-guided catheters carry clot-busting drug to shrink clots, Johns Hopkins-led study shows Johns Hopkins neurologists report success with a new means of getting rid of potentially lethal blood clots in the brain safely without cutting through easily damaged brain tissue or removing large pieces of skull. The minimally invasive treatment, they report, increased the number of patients with intracerebral hemorrhage (ICH) who could function independently by 10 to 15 percent six months...

2012-02-02 18:00:59

Therapeutic cooling for stroke, damaging effects of normally beneficial blood component following ischemic stroke, more Stroke experts from Cedars-Sinai Medical Center will present research updates at the International Stroke Conference of the American Heart Association/American Stroke Association Feb. 1 through Feb. 3 in New Orleans. Highlights include: 6:15 — 6:45 p.m. CST, Feb. 1, Thrombin Activity Associated with Neuronal Damage during Acute Stage of Ischemic Stroke After...

2012-02-02 23:05:40

For patients with a type of irregular heart beat called atrial fibrillation (AF), a new anti-clotting drug might be better at preventing clot-related strokes while minimizing the risk of causing a bleeding stroke. The research was presented at the American Stroke Association's International Stroke Conference 2012. The finding stems from a sub-analysis of data in a large, randomized clinical trial called ROCKET AF, conducted in 45 countries at 1,178 sites. ROCKET AF tested the new drug...


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