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Last updated on April 24, 2014 at 17:35 EDT

Latest Toll-like receptor Stories

Disrupted Sleep Patterns May Accelerate Tumor Growth
2014-01-28 06:29:35

Brett Smith for redOrbit.com - Your Universe Online A new study from a team of American researchers has revealed that a disrupted sleep pattern can accelerate the progression of cancer. According to the team’s report published in the journal Cancer Research, fragmented sleep disrupts a cancer-fighting metabolic pathway – a disruption that could be mitigated through drug therapy. "It's not the tumor, it's the immune system," said study director Dr. David Gozal, chairman of...

2013-03-05 10:44:28

Promising compound may help protect babies during vulnerable window The underdeveloped immune systems of newborns don't respond to most vaccines, leaving them at high risk for infections like rotavirus, pertussis (whooping cough) and pneumococcus. Researchers at Boston Children's Hospital have identified a potent compound that activates immune responses in newborns' white blood cells substantially better than anything previously tested, and that could potentially make vaccines effective...

2013-03-04 16:26:14

Promising compound may help protect babies during vulnerable window BOSTON, March 4, 2013 /PRNewswire-USNewswire/ -- The underdeveloped immune systems of newborns don't respond to most vaccines, leaving them at high risk for infections like rotavirus, pertussis (whooping cough) and pneumococcus. Researchers at Boston Children's Hospital have identified a potent compound that activates immune responses in newborns' white blood cells substantially better than anything previously...

2012-12-18 08:27:29

PRINCETON, N.J., Dec. 18, 2012 /PRNewswire/ -- Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), a development stage biopharmaceutical company, announced today the acquisition of a novel drug technology, known as SGX94, representing a unique approach to modulation of the innate immune system. SGX94 is an innate defense regulator (IDR) that regulates the innate immune system to reduce inflammation, eliminate infection and enhance tissue healing by binding to the pivotal regulatory...

Long-sought Vaccines For Deadly Parasite Closer To Reality According To New Study
2012-12-13 14:18:47

Cell Press [ Watch The Video ] One major cause of illness from food-borne diseases is the parasite Toxoplasma gondii (T. gondii). New insights into how the immune system combats T. gondii are provided in a study published by Cell Press December 13th in the journal Immunity. The findings could lead to the development of long-sought vaccines to protect against T. gondii and related parasites. To fight off pathogens, the immune system relies on Toll-like receptors (TLRs)–a class...

2012-10-01 16:14:50

Researchers at Queen Mary, University of London have discovered how a key molecule controls the body's inflammatory responses. The molecule, known as p110delta, fine-tunes inflammation to avoid excessive reactions that can damage the organism. The findings, published in Nature Immunology today (30 September), could be exploited in vaccine development and new cancer therapies. A healthy immune system reacts to danger signals — from microorganisms such as bacteria and viruses, or from...

2012-09-27 02:26:45

WOONSOCKET, R.I., Sept. 27, 2012 /PRNewswire/ -- MultiCell Technologies, Inc. (OTC Bulletin Board: MCET) is pleased to announce the acceptance by the American Society for Cell Biology® (ASCB®) of abstract "Short Synthetic Double Stranded RNA with Dual Activity - Oncolytic and Immune Modulatory - for Hepatocellular Carcinoma." The preclinical research results will be presented by Anand Ghanekar M.D., Ph.D., Division of Cellular & Molecular Biology, Toronto General...

2012-07-19 12:06:27

When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can lead to excessive inflammation, new research suggests. While learning that lungs perceive the ventilation as an infection, researchers also discovered potential drug targets that might reduce the resulting inflammation - a tiny piece of RNA and two proteins that have roles...

Lack Of Single Protein Results In Persistent Viral Infection
2012-06-13 21:16:44

Scientists from The Scripps Research Institute have shown a single protein can make the difference between an infection clearing out of the body or persisting for life. The results also show where the defects occur in the immune system without the protein and offer the possibility that targeting this signaling pathway could be beneficial for treatment of persistent viral infections in humans. Currently hundreds of millions of people around the world are afflicted with persistent viral...

2012-05-16 02:29:32

WOONSOCKET, R.I., May 16, 2012 /PRNewswire/ -- MultiCell Technologies, Inc. (OTC Bulletin Board: MCET) is pleased to announce representatives from the Company will present preclinical research findings for MCT-465 and MCT-485 at CIMT 2012 (http://meeting.cimt.eu), Europe's largest meeting dedicated to cancer immunotherapy research and development. CIMT 2012 will be held in May 23-25 in Mainz, Germany. The title of the poster presentation is: "Sharply discordant biological properties of...