Quantcast

Latest Toll-like receptor Stories

2008-10-16 09:00:43

Idera Pharmaceuticals, Inc. (NASDAQ: IDRA) today announced that it will present preclinical data from studies on its autoimmune disease program at the 4th Annual Meeting of the Oligonucleotide Therapeutics Society being held at the Harvard Medical School Conference Center in Boston, October 15-18, 2008. The Company's presentations describe studies of novel compounds targeted to Toll-like Receptors (TLRs), including the evaluation of TLR antagonist compounds in preclinical models of autoimmune...

2008-09-03 09:00:00

PHILADELPHIA, Sept. 3, 2008 (GLOBE NEWSWIRE) -- Hemispherx Biopharma, Inc. (AMEX:HEB) today announced that the Company will present at the BioPharm America Conference to be held on September 9 to 10, 2008 at the Grand Hyatt, Atlanta, GA. The oral presentation, "TLRs: New Targets for Broad-Based Pharmaceutical Development," is scheduled for Wednesday, September 10 at 3:30PM. NDA Status: Chronic Fatigue Syndrome Treatment Currently, the only TLR3 ligand in a completed...

3c5b63d2075c2c9271ec4ed35994a5c41
2008-04-17 13:40:00

Austrian scientists identify the common mechanism underlying acute respiratory disease syndrome ARDSThe Spanish flu outbreak of 1918 killed between 30 and 50 million people. In the infected patients, the ultimate cause of death was acute respiratory distress syndrome (ARDS). This fatal condition is a massive reaction of the body during which the lung becomes severely damaged. ARDS can be induced by various bacterial and viral infections, but also by chemical agents. These could be toxic gases...

2005-12-07 16:58:55

A new study finds that a gene which plays an important role in immune function, known as toll-like receptor 4 (TLR4), may also play a critical role in suppressing chronic lung inflammation and tumor development in mice. "We know that chronic inflammation predisposes people to many types of cancer," says NIH Director Elias Zerhouni, M.D. "By using this new information we may be able to suppress chronic inflammation and reduce our Nation's cancer burden." In the December 7, 2005 issue of the...

2005-08-23 13:35:00

Researchers at the University of Pennsylvania School of Medicine have published the first study to test the role of RNA chemical modifications on immunity. They have demonstrated that RNA from bacteria stimulates immune cells to orchestrate destruction of invading pathogens. Most RNA from human cells is recognized as being self and does not stimulate an immune response to the same extent as invading bacteria or viruses. The researchers hypothesize that if this self-recognition fails, then...

2005-06-20 13:15:00

La Jolla, CA, June 20, 2005 - Scientists at The Scripps Research Institute have solved the structure of a crucial human immune system molecule called TLR3, an acronym for Toll-like receptor three. In an upcoming issue of the journal Science, the protein is described as a large horseshoe-shaped coil composed of 23 leucine-rich repeats (LRRs). The structure reveals details of TLR3 that have never been seen before, an essential step toward fully understanding the critical role this...

2005-05-27 22:55:00

Boston, MA - With the unusual opportunity that human leprosy infections provide for study of human immune responses, scientists have discovered how the body's early warning system prompts a rapid immune response by two separate armies of defensive cells. The finding helps explain why, when threatened by microbes like the leprosy bug, this initial defense sometimes succeeds in limiting the damage, but in other cases yields to a dangerous, spreading infection. Led by Stephan R. Krutzik of UCLA,...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
Related