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How An Ancient Vertebrate Uses Familiar Tools To Build A

How An Ancient Vertebrate Uses Familiar Tools To Build A Strange-Looking Head

Kim Bland, Ph.D., Stowers Institute for Medical Research Sea lamprey studies show remarkably conserved gene expression patterns in jawless versus jawed vertebrates If you never understood what “ontogeny recapitulates phylogeny” meant in...

Latest Transcription factors Stories

2014-09-18 23:08:33

New Assay to Test Target Compounds for Anti-Obesity Therapeutics State College, PA (PRWEB) September 18, 2014 INDIGO Biosciences, a leading provider of nuclear receptor products and services announced today that it has released a new Human Estrogen-related Orphan Receptor Gamma (NR3B3; ERRγ) Assay System. Three different assay kits are available. ERRγ is naturally expressed in the central nervous system, and at lower relative levels in a variety of other tissue types, including kidney,...

autism estrogen
2014-09-10 06:19:41

Chuck Bednar for redOrbit.com - Your Universe Online The reason that girls are less likely than boys to suffer from autism may have something to do with the same sex hormone receptor responsible for helping protect them from stroke, according to new research published Tuesday in the journal Molecular Autism. In what is being called the first analysis of the role of estrogen in autism, experts from the Medical College of Georgia at Georgia Regents University examined the brains of people...

2014-08-18 23:06:24

New Human Aryl Hydrocarbon Receptor Reporter Assay System Kit State College, PA (PRWEB) August 18, 2014 INDIGO Biosciences, a research products and services company focused on nuclear receptor screenings, announced today that it has released new cell-based Aryl Hydrocarbon Receptor (AhR) reporter assay kits. The Aryl Hydocarbon Recepctor (AhR) Assay employs the luciferase reporter gene technology, and is used for screening test samples to quantify any functional activity that they may...

2014-08-18 08:28:34

Proceedings of the National Academy of Sciences Study Shows Ability to Create Therapeutics Targeting Critical MYC Regulator for Potential Treatment of Cancer SAN DIEGO, Aug. 18, 2014 /PRNewswire/ -- Sorrento Therapeutics, Inc. (NASDAQ: SRNE; Sorrento), a late-stage clinical oncology company developing new treatments for cancer and its associated pain, today announced that data published in the Proceedings of the National Academy of Sciences (PNAS)(1) demonstrate the potential for the...

2014-07-10 12:34:40

Centro Nacional de Investigaciones Oncologicas (CNIO) The pluripotency factor NANOG regulates cell proliferation in epithelia of the skin and oesophagus in adult organisms; blocking the action of the gene diminishes the capacity of tumour cells to divide Scientists from the Spanish National Cancer Research Centre (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia—those that form part of the epidermis of...

2014-06-25 11:27:24

University of Minnesota Gene partnership may be fueling cancer spread in as much as 20 percent of cancers A key cancer-causing gene, responsible for up to 20 percent of cancers, may have a weak spot in its armor, according to new research from the Masonic Cancer Center, University of Minnesota. The partnership of MYC, a gene long linked to cancer, and a non-coding RNA, PVT1, could be the key to understanding how MYC fuels cancer cells. The research is published in the latest issue...

2014-05-29 04:21:56

AHMEDABAD, India, May 29, 2014 /PRNewswire/ -- Commences Phase III trials of Lipaglyn(TM) (Saroglitazar) in patients suffering from Lipodystrophy Exploring newer therapeutic usage of its breakthrough drug Lipaglyn(TM) (Saroglitazar), the Zydus Group has now initiated Phase III trials of the molecule for patients suffering from lipodystrophy. The drug is already approved in India for treating diabetic dyslipidemia and hypertriglyceridemia. The goal of this trial is to...

2014-05-27 15:08:14

EMBL How long-distance control impacts face formation Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face. The study, published today in Nature Genetics, helps understand the genetic causes of cleft lip and cleft palate, which are among the most common congenital malformations in humans. “This genomic region ultimately controls genes which determine...

2014-05-12 11:33:31

Whitehead Institute for Biomedical Research Whitehead Institute scientists have identified a genetic cause of a facial disorder known as hemifacial microsomia (HFM). The researchers find that duplication of the gene OTX2 induces HFM, the second-most common facial anomaly after cleft lip and palate. HFM affects approximately one in 3,500 births. While some cases appear to run in families, no gene had been found to be causative. That is until Whitehead Fellow Yaniv Erlich and his lab set...

2014-05-07 08:32:14

First-in-class DOT1L Inhibitor in Clinical Development as Potential Personalized Therapeutic for Patients with Genetically Defined Acute Leukemias CAMBRIDGE, Mass., May 7, 2014 /PRNewswire/ -- Epizyme, Inc. (NASDAQ: EPZM), a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, today announced the initiation of a Phase 1b open-label clinical study of EPZ-5676 in pediatric patients with acute leukemias...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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