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2014-08-18 23:06:24

New Human Aryl Hydrocarbon Receptor Reporter Assay System Kit State College, PA (PRWEB) August 18, 2014 INDIGO Biosciences, a research products and services company focused on nuclear receptor screenings, announced today that it has released new cell-based Aryl Hydrocarbon Receptor (AhR) reporter assay kits. The Aryl Hydocarbon Recepctor (AhR) Assay employs the luciferase reporter gene technology, and is used for screening test samples to quantify any functional activity that they may...

2014-08-18 08:28:34

Proceedings of the National Academy of Sciences Study Shows Ability to Create Therapeutics Targeting Critical MYC Regulator for Potential Treatment of Cancer SAN DIEGO, Aug. 18, 2014 /PRNewswire/ -- Sorrento Therapeutics, Inc. (NASDAQ: SRNE; Sorrento), a late-stage clinical oncology company developing new treatments for cancer and its associated pain, today announced that data published in the Proceedings of the National Academy of Sciences (PNAS)(1) demonstrate the potential for the...

2014-07-10 12:34:40

Centro Nacional de Investigaciones Oncologicas (CNIO) The pluripotency factor NANOG regulates cell proliferation in epithelia of the skin and oesophagus in adult organisms; blocking the action of the gene diminishes the capacity of tumour cells to divide Scientists from the Spanish National Cancer Research Centre (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia—those that form part of the epidermis of...

2014-06-25 11:27:24

University of Minnesota Gene partnership may be fueling cancer spread in as much as 20 percent of cancers A key cancer-causing gene, responsible for up to 20 percent of cancers, may have a weak spot in its armor, according to new research from the Masonic Cancer Center, University of Minnesota. The partnership of MYC, a gene long linked to cancer, and a non-coding RNA, PVT1, could be the key to understanding how MYC fuels cancer cells. The research is published in the latest issue...

2014-05-29 04:21:56

AHMEDABAD, India, May 29, 2014 /PRNewswire/ -- Commences Phase III trials of Lipaglyn(TM) (Saroglitazar) in patients suffering from Lipodystrophy Exploring newer therapeutic usage of its breakthrough drug Lipaglyn(TM) (Saroglitazar), the Zydus Group has now initiated Phase III trials of the molecule for patients suffering from lipodystrophy. The drug is already approved in India for treating diabetic dyslipidemia and hypertriglyceridemia. The goal of this trial is to...

2014-05-27 15:08:14

EMBL How long-distance control impacts face formation Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face. The study, published today in Nature Genetics, helps understand the genetic causes of cleft lip and cleft palate, which are among the most common congenital malformations in humans. “This genomic region ultimately controls genes which determine...

2014-05-12 11:33:31

Whitehead Institute for Biomedical Research Whitehead Institute scientists have identified a genetic cause of a facial disorder known as hemifacial microsomia (HFM). The researchers find that duplication of the gene OTX2 induces HFM, the second-most common facial anomaly after cleft lip and palate. HFM affects approximately one in 3,500 births. While some cases appear to run in families, no gene had been found to be causative. That is until Whitehead Fellow Yaniv Erlich and his lab set...

2014-05-07 08:32:14

First-in-class DOT1L Inhibitor in Clinical Development as Potential Personalized Therapeutic for Patients with Genetically Defined Acute Leukemias CAMBRIDGE, Mass., May 7, 2014 /PRNewswire/ -- Epizyme, Inc. (NASDAQ: EPZM), a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, today announced the initiation of a Phase 1b open-label clinical study of EPZ-5676 in pediatric patients with acute leukemias...

2014-04-28 12:17:35

The discovery of an unknown cellular pathway has helped scientists and physicians better understand end-stage liver disease and offers a potential target for new therapeutics A team of researchers in the University of Arizona's College of Pharmacy has discovered a molecular pathway that could be key to creating new therapeutics that would slow or even reverse the progression of end-stage liver disease. Although cirrhosis of the liver is most commonly associated with alcohol or drug...

2014-04-16 10:13:27

All organisms, from mammals to fungi, have daily cycles controlled by a tightly regulated internal clock, called the circadian clock. The whole-body circadian clock, influenced by the exposure to light, dictates the wake-sleep cycle. At the cellular level, the clock is controlled by a complex network of genes and proteins that switch each other on and off based on cues from their environment. Most genes involved in the regulation of the circadian clock have been characterized, but Akihiro...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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