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Latest Transcription factors Stories

2013-11-13 13:27:31

A class of drugs used to treat parasitic infections such as malaria may also be useful in treating cancers and immune-related diseases, a new WSU-led study has found. Researchers discovered that simple modifications to the drug furamidine have a major impact on its ability to affect specific human proteins involved in the on-off switches of certain genes. “This was rather unexpected, given how relatively simple the molecules are that we modified and how difficult it has been to affect...

2013-10-30 15:38:23

A new study by Weill Cornell Medical College scientists reveals a mechanism through which the expression of genes is controlled -- a finding that highlights genetic mutations that can impair the timing of gene expression. Such mutations can affect the co-ordination of key events that are required for stepwise development of an organism, and can also give rise to cancer by turning on genes at the wrong time. The study, published October 29 in the open access journal PLOS Biology, analyzes...

Mechanism Through Which The Expression Of Genes Is Controlled Revealed
2013-10-30 08:58:05

Public Library of Science A new study by Weill Cornell Medical College scientists reveals a mechanism through which the expression of genes is controlled – a finding that highlights genetic mutations that can impair the timing of gene expression. Such mutations can affect the co-ordination of key events that are required for stepwise development of an organism, and can also give rise to cancer by turning on genes at the wrong time. The study, published October 29 in the open access...

Gene Enhancers Play Major Role In Making Our Faces Unique
2013-10-25 07:52:51

[ Watch the Video: Face It - We All Look Different ] April Flowers for redOrbit.com - Your Universe Online No two faces look exactly alike, making the human face as unique as a fingerprint. What makes facial morphology so distinct, though? Genetics obviously plays a major role, as is evident in the similarities between parents and children. But what in our DNA fine-tunes the genetics so that siblings, especially identical twins, resemble one another but look different from unrelated...

2013-10-14 11:18:08

Researchers identify key proteins that help establish cell function Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off. Writing in the October 13, 2013 Advance Online Publication of Nature, the scientists say their approach could make it quicker and easier to identify specific gene mutations associated with...

2013-09-30 14:04:37

Weizmann Institute researchers discover that a “standoff” between a mutated gene and its normal counterpart keeps certain cancer cells alive What keeps leukemia cells alive almost forever, able to continue dividing endlessly and aggressively? New research at the Weizmann Institute suggests that, in around a quarter of all leukemias, the cancer cells rely on an internal “balance of terror” to keep going. When one version of a certain gene is mutated, it becomes a cancer-promoting...

2013-09-20 11:25:30

Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic biomarker for identifying smoking-related lung cancers. The protein — ASCL1 — is associated with increased expression of the RET oncogene, a particular cancer-causing gene called RET. The findings appear in the online issue of the journal Oncogene. "This is exciting because we've found what we believe to be a 'drugable target' here," says George Vasmatzis, Ph.D., a Mayo Clinic molecular...

2013-09-09 04:20:03

Discovery of RNA regulator could lead to a better understanding of diseases like cancer and influenzaSingapore, Sept 9, 2013 - (ACN Newswire) - Scientists at A*STAR's Genome Institute of Singapore (GIS), in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning of human embryonic stem cells (hESCs). This finding was reported on 8th September 2013 in the...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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