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2013-11-25 14:40:21

2 separate studies yield key findings for the prevention, diagnosis, treatment and cure for the disease Acute myeloid leukemia (AML) is a group of heterogeneous diseases with considerable diversity in terms of genetic abnormalities. Mutations of CEBPA, a tumour suppressor, are found in about 10 per cent of human AML patients. In two separate studies on CEBPA mutations in AML subtypes, researchers successfully identified and validated a gene known as Sox4 as a potential therapeutic target...

Genetic Variant Linked To Freckling, Sun Sensitivity Discovered
2013-11-22 08:16:48

[ Watch the Video: Genetic Variant Linked To Freckling And Sun Sensitivity ] April Flowers for redOrbit.com - Your Universe Online A genomic variant strongly associated with sensitivity to the sun, brown hair, blue eyes and freckles has been identified by a new study. Researchers studying Icelanders discovered an intricate pathway involving the interspersed DNA sequence, or non-coding region, of a gene that is among a few dozen that are associated with human pigmentation traits. The...

2013-11-21 13:07:01

Gene found in human speech problems affects singing, not learning in songbirds A genetic defect that profoundly affects speech in humans also disrupts the ability of songbirds to sing effective courtship tunes. This defect in a gene called FoxP2 renders the brain circuitry insensitive to feel-good chemicals that serve as a reward for speaking the correct syllable or hitting the right note, a recent study shows. The research, which was conducted in adult zebrafinches, gives insight into...

2013-11-13 13:27:31

A class of drugs used to treat parasitic infections such as malaria may also be useful in treating cancers and immune-related diseases, a new WSU-led study has found. Researchers discovered that simple modifications to the drug furamidine have a major impact on its ability to affect specific human proteins involved in the on-off switches of certain genes. “This was rather unexpected, given how relatively simple the molecules are that we modified and how difficult it has been to affect...

2013-10-30 15:38:23

A new study by Weill Cornell Medical College scientists reveals a mechanism through which the expression of genes is controlled -- a finding that highlights genetic mutations that can impair the timing of gene expression. Such mutations can affect the co-ordination of key events that are required for stepwise development of an organism, and can also give rise to cancer by turning on genes at the wrong time. The study, published October 29 in the open access journal PLOS Biology, analyzes...

Mechanism Through Which The Expression Of Genes Is Controlled Revealed
2013-10-30 08:58:05

Public Library of Science A new study by Weill Cornell Medical College scientists reveals a mechanism through which the expression of genes is controlled – a finding that highlights genetic mutations that can impair the timing of gene expression. Such mutations can affect the co-ordination of key events that are required for stepwise development of an organism, and can also give rise to cancer by turning on genes at the wrong time. The study, published October 29 in the open access...

Gene Enhancers Play Major Role In Making Our Faces Unique
2013-10-25 07:52:51

[ Watch the Video: Face It - We All Look Different ] April Flowers for redOrbit.com - Your Universe Online No two faces look exactly alike, making the human face as unique as a fingerprint. What makes facial morphology so distinct, though? Genetics obviously plays a major role, as is evident in the similarities between parents and children. But what in our DNA fine-tunes the genetics so that siblings, especially identical twins, resemble one another but look different from unrelated...

2013-10-14 11:18:08

Researchers identify key proteins that help establish cell function Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off. Writing in the October 13, 2013 Advance Online Publication of Nature, the scientists say their approach could make it quicker and easier to identify specific gene mutations associated with...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'