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First Estrogen Receptor Mutation Identified In A Young Woman
2013-07-11 13:00:14

Medical College of Georgia at Georgia Regents University A receptor mutation that essentially blocks estrogen's action has been identified for the first time in a female, researchers report. The 18-year-old wasn't experiencing breast development or menstruation, classic symptoms of too little estrogen, the usual cause of delayed puberty. Subsequent studies revealed instead sky-high levels of the sex hormone in her blood, said Dr. Lawrence C. Layman, Chief of the Section of Reproductive...

2013-06-19 14:29:34

Gladstone-led study sheds light on molecular basis for metabolic health and disease Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called "circadian clock" are complex, and the molecular processes behind it have long eluded scientists. But now, researchers at the Gladstone Institutes have discovered how one important protein falls under direct instructions from the body's circadian clock....

2013-06-18 13:52:00

-A protein called Nanog helps the renewal of healthy embryonic stem cells. -This study shows that Nanog also promotes cancer stem cell proliferation in head and neck cancer and shows how it promotes their growth. -The findings could lead to new, novel treatments for head and neck cancer. A new study led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) has...

2013-06-03 23:17:40

Scientists from Peking University, China and OriGene Technologies jointly published that multiple lineage specifier genes can replace OCT4 and SOX2, the core regulators of cell pluripotency. The results were published in the May 23rd issue of Cell, titled “Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers”. Rockville, MD (PRWEB) June 03, 2013 Scientists from Peking University, China and OriGene Technologies jointly published that multiple lineage specifier...

2013-05-09 23:04:11

A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing them to fend off stress, says a University of Colorado Boulder study. Boulder, CO (PRWEB) May 09, 2013 A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing...

2013-05-08 17:53:05

An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells contain abnormally high levels of the pro-growth protein Stat5. They discovered that the gene that makes the protein is amplified – duplicated many times over – in these cancer cells, which allows them to produce excess amounts of the oncogenic protein....


Word of the Day
pungle
  • To take pains; labor assiduously with little progress.
This word comes from the Spanish 'pongale,' put it.
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