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Latest Transdifferentiation Stories

Researchers Discover How To Change Cell Types By Flipping A Single Switch
2013-12-04 13:05:09

University of California - Santa Barbara With few exceptions, cells don't change type once they have become specialized — a heart cell, for example, won't suddenly become a brain cell. However, new findings by researchers at UC Santa Barbara have identified a method for changing one cell type into another in a process called forced transdifferentiation. Their work appears today in the journal Development. With C. elegans as the animal model, lead author Misty Riddle, a Ph.D. student...

2013-06-20 12:03:57

Studies in zebrafish reveal abundant potential source for repair of injured heart muscle In a study published in the June 19 online edition of the journal Nature, a scientific team led by researchers from the University of California, San Diego School of Medicine visually monitored the dynamic cellular events that take place when cardiac regeneration occurs in zebrafish after cardiac ventricular injury. Their findings provide evidence that various cell lines in the heart are more plastic,...

2005-08-06 15:24:52

There is disagreement, however, about the mechanism on which repair processes are based. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, in co-operation with colleagues from Martin Luther University in Halle-Wittenberg, have now shown that skeletal muscle tissue can fuse with adult stem cells, via a mechanism based on the participation of mediators which are generally involved in immune cell activation. Although being unable to transdifferentiate...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'