Latest Transforming growth factor beta Stories

Findings suggest VEGF inhibition via TGF-B1 may be beneficial The most common cause of failure after glaucoma surgery is scarring at the surgical site, so researchers are actively looking for ways to minimize or prevent scar formation. Previous work had suggested that vascular endothelial growth factor (VEGF) activates fibrosis, whereas VEGF inhibition results in reduced scar formation and better surgical results. In a series of studies using a rabbit model of glaucoma surgery,...

Diverse pipeline reflected in four molecules targeting key cancer pathways WASHINGTON, April 10, 2013 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) unveiled data from four key molecules that represent the next generation of its oncology pipeline at the American Association for Cancer Research (AACR) Annual Meeting held in Washington, D.C. from April 6-10. The data reflect Lilly's diverse oncology pipeline via molecules that target several pathways that are among the most common...

Institute for Research in Biomedicine (IRB Barcelona) The study, published in the prestigious journal Cancer Cell, reveals that tumor cells of the colon must form alliances with healthy cells in order to colonize other organs during metastasis A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability of colon cancer to metastasize lies in...