Quantcast

Latest Transgenerational epigenetics Stories

2014-07-28 10:39:26

Baylor College of Medicine Cancer has long been thought to be primarily a genetic disease, but in recent decades scientists have come to believe that epigenetic changes – which don't change the DNA sequence but how it is 'read' – also play a role in cancer. In particular DNA methylation, the addition of a methyl group (or molecule), is an epigenetic switch that can stably turn off genes, suggesting the potential to cause cancer just as a genetic mutation can. Until now, however,...

dna single-cell technique
2014-07-22 03:30:21

Biotechnology and Biological Sciences Research Council (BBSRC) Researchers develop new, powerful single-cell technique to study environmental effects on DNA Researchers at the BBSRC-funded Babraham Institute, in collaboration with the Wellcome Trust Sanger Institute Single Cell Genomics Centre, have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents. The technique can be used to map...

2014-07-11 10:58:16

University of Cambridge When a pregnant mother is undernourished, her child is at a greater than average risk of developing obesity and type 2 diabetes, in part due to so-called 'epigenetic' effects. A new study in mice demonstrates that this 'memory' of nutrition during pregnancy can be passed through sperm of male offspring to the next generation, increasing risk of disease for her grandchildren as well. In other words, to adapt an old maxim, 'you are what your grandmother ate'. The...

2014-02-10 11:03:42

A Lawrence Livermore National Laboratory physicist and his colleagues have found a new application for the tools and mathematics typically used in physics to help solve problems in biology. Specifically, the team used statistical mechanics and mathematical modeling to shed light on something known as epigenetic memory -- how an organism can create a biological memory of some variable condition, such as quality of nutrition or temperature. "The work highlights the interdisciplinary...

Environment, Lifestyle Factors Determines Changes In Pain Sensitivity
2014-02-05 09:12:41

Ranjini Raghunath for redOrbit.com - Your Universe Online The way you react to pain keeps changing throughout your lifetime, influenced by lifestyle and environmental factors, a new study carried out by researchers at King’s College London suggests. The study identified genetic changes that determine how different people – even identical twins -- react to pain differently. The results from the study could help scientists understand how pain sensitivity differs in individuals, and...

2013-09-24 09:44:43

USC microbiologists describe how 'natural killer' cells depend on enzyme to develop Natural killer (NK) cells in the human body can kill and contain viruses and cancerous tumors, and a new study from the University of Southern California (USC) describes for the first time how those cells can be manipulated by epigenetics. The discovery, detailed in the Proceedings of the National Academy of Sciences, paves the way for developing more effective cancer drugs. "Natural killer cells are...

2013-07-23 13:31:35

New technique can rapidly turn genes on and off, helping scientists better understand their function. Although human cells have an estimated 20,000 genes, only a fraction of those are turned on at any given time, depending on the cell’s needs — which can change by the minute or hour. To find out what those genes are doing, researchers need tools that can manipulate their status on similarly short timescales. That is now possible, thanks to a new...

2013-02-08 13:48:51

Epigenetic investigation of mice can as a result contribute to early diagnosis of cancer in humans Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between the genetic and epigenetic mechanisms is critical for the selection of tumor biomarkers and for the future development of therapies. Human tumor specimens and cell lines however contain a...

2012-10-01 16:28:13

Over the last two decades, scientists have come to understand that the genetic code held within DNA represents only part of the blueprint of life. The rest comes from specific patterns of chemical tags that overlay the DNA structure, determining how tightly the DNA is packaged and how accessible certain genes are to be switched on or off. As researchers have uncovered more and more of these "epigenetic" tags, they have begun to wonder how they are all connected. Now, research from the...

2011-06-30 18:16:25

New research in the FASEB Journal shows that epigenetics affects whether or not stem cells differentiate Adult stem cells and progenitor cells may not come with a clean genetic slate after all. That's because a new report in the FASEB Journal (http://www.fasebj.org) shows that adult stem or progenitor cells have their own unique "epigenetic signatures," which change once a cell differentiates. This is important because epigenetic changes do not affect the actual make up in a cell's DNA,...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
Related