Quantcast

Latest Transient receptor potential cation channel, member A1 Stories

2014-09-17 12:27:24

MUMBAI, India, September 17, 2014 /PRNewswire/ -- - Glenmark's first in class TRPA1 antagonist, GRC 17536, has shown positive data in a Phase 2a proof of concept study in patients with painful diabetic neuropathy Glenmark Pharmaceuticals today announced that its first in class Transient Receptor Potential Ankyrin 1 (TRPA1) antagonist, GRC 17536 has shown positive data in a Phase 2a double blind, placebo controlled, multi-centre, proof of concept...

Improving The Skin's Response To UVA Light
2013-01-22 05:41:26

April Flowers for redOrbit.com - Your Universe Online A group of researchers from Brown University have demonstrated that certain skin cells use a light-sensitive receptor found outside of the eye to detect ultraviolet light and quickly begin producing melanin to prevent DNA damage. The same team, in a new study published in Proceedings of the National Academy of Sciences, has identified a key player in that biomolecular chain of events that could become a pharmacological target for...

2011-12-15 16:26:29

A discovery in fruit flies may be able to tell us more about how animals, including humans, sense potentially dangerous discomforts. Researchers at Duke University Medical Center uncovered naturally occurring variations of a gene named TRPA1 that is important for the function of pain-sensing neurons throughout the animal kingdom. The gene makes an ion channel, which floods sensory neurons with calcium ions when the fly is near a heat source, causing fruit fly larvae to respond with a...

Addressing Pain And Disease On The Fly
2011-12-07 09:29:43

How fruit flies can teach us about curing chronic pain and halting mosquito-borne diseases Studies of a protein that fruit flies use to sense heat and chemicals may someday provide solutions to human pain and the control of disease-spreading mosquitoes. In the current issue of the journal Nature, biologist Paul Garrity of the National Center for Behavioral Genomics at Brandeis University and his team, spearheaded by KyeongJin Kang and Vince Panzano in the Garrity lab, report how fruit...

2011-12-05 13:02:56

Fruit fly and malaria mosquito sensors attuned to heat, chemical odors Fruit flies and mosquitoes share similar sensory receptors that allow them to distinguish among thousands of sensory cues — particularly heat and chemical odors — as they search for food or try to avoid danger, researchers from Boston College and Brandeis University report in the current electronic edition of the journal Nature. Pinpointing a tiny portion of a protein found on the surfaces of neurons that...

2011-11-22 17:26:52

Researchers at King's College London have discovered how one of the most common household painkillers works, which could pave the way for less harmful pain relief medications to be developed in the future Researchers at King's College London have discovered how one of the most common household painkillers works, which could pave the way for less harmful pain relief medications to be developed in the future. Paracetamol, often known in the US and Asia as acetaminophen, is a widely-used...

2011-03-11 15:40:41

New research from Mount Sinai School of Medicine has discovered that rhodopsin, a pigment of the retina that is responsible for the first events in the perception of light, may also be involved in temperature sensation. This detection had not been revealed in previous studies. The work emerged from a collaboration between the laboratory of Andrew Chess, M.D., Professor in the Departments of Neuroscience, Developmental and Regenerative Biology and Genetics and Genomic Sciences at Mount Sinai,...

2011-03-10 23:26:21

A light-sensing receptor that's packed inside the eye's photoreceptor cells has an altogether surprising role in cells elsewhere in the body, Johns Hopkins scientists have discovered. Using fruit flies, they showed that this protein, called rhodopsin, also is critical for sensing temperature. A report on the work appears March 11 in Science. "For decades, this well-known molecule "” one of the most-studied sensory receptors "” was thought to function exclusively in the eye as a...

2011-01-19 13:20:39

Combination of sensory and molecular approaches identify receptor sensitive to anti-inflammatory compounds Scientists from the Monell Center and collaborators report that a receptor known as TRPA1 is activated by two structurally unrelated anti-inflammatory compounds. The first, oleocanthal, is a natural polyphenolic anti-inflammatory agent uniquely found in extra virgin olive oil; while the second, ibuprofen, is an over-the-counter non-steroidal anti-inflammatory drug (NSAID). The...

d92731a2d5fb515057c08e5fa567343a1
2010-09-29 09:25:00

Fizzy beverages light up same pain sensors as mustard and horseradish, a new study shows -- so why do we drink them? You may not think of the fizz in soda as spicy, but your body does. The carbon dioxide in fizzy drinks sets off the same pain sensors in the nasal cavity as mustard and horseradish, though at a lower intensity, according to new research from the University of Southern California. "Carbonation evokes two distinct sensations. It makes things sour and it also makes them burn. We...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
Related