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Latest Transmembrane protein Stories

2012-06-11 21:50:23

Researchers work to untangle knots, slipknots in species separated by a billion years of evolution Strings of all kinds, when jostled, wind up in knots. It turns out that happens even when the strings are long strands of molecules that make up proteins. A new study by scientists at Rice University and elsewhere examines structures of proteins that not only twist and turn themselves into knots, but also form slipknots that, if anybody could actually see them, might look like shoelaces...

2012-06-05 10:01:37

A new study suggests that protein knots, a structure whose formation remains a mystery, may have specific functional advantages that depend on the nature of the protein's architecture. "The presence of a knotted or slipknotted structure in a protein is relatively rare but really is very interesting," said Kenneth Millett, a professor of mathematics at UC Santa Barbara and a co-author of the paper, "Conservation of complex knotting and slipknotting patterns in proteins," published in the...

2011-06-15 21:16:51

Plant receptors use different signalling method than do animal receptors Every living plant cell and animal cell is surrounded by a membrane. These cellular membranes contain receptor molecules that serve as the cell's eyes and ears, and help it communicate with other cells and with the outside world. The receptor molecules accomplish three basic things in the communication process: 1) recognize an outside signal, 2) transport that signal across the cell's membrane and 3) initiate the reading...

2011-02-23 13:55:29

Scientists at IRB Barcelona resolve a three-dimensional structure required for the function of some vital cell transporters which communicate cells with the external environment. This finding will contribute to understanding some of the functional disruptions caused by human diseases. Researchers at IRB Barcelona have completed the 3D structural sequence adopted by several essential proteins in the exchange of substances between the extra and intracellular milieu. This finding provides a...

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2011-02-08 07:38:20

Berkeley Lab Reports New Fluorescent Assay Reveals TREK1 Mechanism By Lynn Yarris, Berkeley Lab Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel. TREK1 activity has been...

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2010-12-15 07:46:02

They say it's the little things that count, and that certainly holds true for the channels in transmembrane proteins, which are small enough to allow ions or molecules of a certain size to pass through, while keeping out larger objects. Artificial fluidic nanochannels that mimic the capabilities of transmembrane proteins are highly prized for a number of advanced technologies. However, it has been difficult to make individual artificial channels of this size "“ until now. Researchers...

2010-10-19 17:00:25

US, Argentinean scientists: Bacteria respond indirectly to cold Some bacteria react to the cold by subtly changing the chemistry of their outer wall so that it remains pliable as temperatures drop. Scientists identified a key protein in this response mechanism a few years ago, but the question of how bacteria sense cold in the first place remained a mystery. Based on a study by scientists at Rice University and Argentina's National University of Rosario, the answer is: They use a measuring...

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2009-02-17 09:27:58

A more specific and faster detection of viruses has been identified in new research by Trinity College Dublin's Professor of Physics, Martin Hegner at Trinity College's Center of Research on Adaptive Nanostructures and Nanodevices (CRANN) and an international team of researchers. These findings have been published online in Nature News and will be published in the international peer-reviewed journal Nature Nanotechnology in March. Viruses can be now detected in fluids and their detection is...

2005-09-19 16:10:00

HOUSTON -- It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered. New research from Rice University offers clues, showing for the first time how salicylate -- an active metabolite of aspirin -- weakens lipid membranes. Researchers believe these mechanical changes disrupt the lining of the stomach, which functions to protect underlying tissue from the acidic contents of...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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