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Latest Transmembrane receptors Stories

2014-03-26 11:18:13

The problems people with autism have with memory formation, higher-level thinking and social interactions may be partially attributable to the activity of receptors inside brain cells, researchers at Washington University School of Medicine in St. Louis have learned. Scientists were already aware that the type of receptor in question was a potential contributor to these problems – when located on the surfaces of brain cells. Until now, though, the role of the same type of receptor...

How Membrane Transporter Moves
2013-12-03 09:50:42

University of Illinois Researchers have tried for decades to understand the undulations and gyrations that allow transport proteins to shuttle molecules from one side of a cell membrane to the other. Now scientists report that they have found a way to penetrate the mystery. They have worked out every step in the molecular dance that enables one such transporter to do its job. The new findings, reported in the Proceedings of the National Academy of Sciences, will help scientists figure...

2013-10-07 13:50:24

This press release is in support of a presentation by Dr. Benoit Delatour on Monday Oct. 7 at the 26th ECNP Congress in Barcelona, Spain A selective GABA inverse agonist has restored cognitive function in a mouse model of Down's syndrome (DS) and has the potential to benefit humans, French researchers have revealed. "The drug we used is a specific GABA-A α5 inverse agonist (α5IA) that hypothetically could combat the abnormal neuronal excitation/inhibition balance associated with DS",...

2013-06-25 13:15:33

Glutamate-like receptor in Arabidopsis does not detect glutamate Plants possess receptors which are similar to the glutamate receptors in the brain of humans and animals. Biochemists at the Ruhr-Universität Bochum (RUB) with colleagues from the University of Würzburg and the Agricultural University of China in Beijing have discovered that these receptors do not, however, recognize the amino acid glutamate, but many other different amino acids. The team reports in the journal "Science...

2012-12-11 21:38:00

A new study published in Biological Psychiatry suggests that autism is associated with reductions in the level of cellular adhesion molecules in the blood, where they play a role in immune function. Cell adhesion molecules are the glue that binds cells together in the body. Deficits in adhesion molecules would be expected to compromise processes at the interfaces between cells, influencing tissue integrity and cell-to-cell signaling. In the brain, deficits in adhesion molecules could...

2012-08-29 07:01:39

Proteins adorning the surfaces of human cells perform an array of essential functions, including cell signaling, communication and the transport of vital substances into and out of cells. They are critical targets for drug delivery and many proteins are now being identified as disease biomarkers–early warning beacons announcing the pre-symptomatic presence of cancers and other diseases. While study of the binding properties of membrane proteins is essential, detailed analysis of...

New Model Synapse Could Help With Disorders Such As Epilepsy And Anxiety
2012-08-08 09:42:42

A new way to study the role of a critical neurotransmitter in disorders such as epilepsy, anxiety, insomnia, depression, schizophrenia, and alcohol addiction has been developed by a group of scientists led by Gong Chen, an associate professor of biology at Penn State University. The new method involves molecularly engineering a model synapse -- a structure through which a nerve cell sends signals to another cell. This model synapse can precisely control a variety of receptors for the...

2012-06-18 11:01:12

Researchers at Baylor College of Medicine and Texas Children's Hospital have identified commensal bacteria in the human intestine that produce a neurotransmitter that may play a role in preventing or treating inflammatory bowel diseases such as Crohn's disease. "We identified, to our knowledge, the first bifidobacterial strain, Bifidobacterium dentium, that is capable of secreting large amounts of gamma-aminobutyric acid (GABA). This molecule is a major inhibitory neurotransmitter in the...

2012-02-01 23:36:46

Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules -- potentially leading to new ways to treat or prevent diseases such as breast cancer and Alzheimer's disease. The findings appear in the latest issues of the journals Nature and Journal of Biological Chemistry. "These are exquisite three-dimensional objects, and the structures...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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