Latest trials Stories
California Pacific Medical Center Research Institute investigators and colleagues provide a snapshot of registered clinical trials and a scorecard of publicly available results San
While the FDA requires that sponsors and clinical investigators register all applicable clinical trials and report the results of these trials on the ClinicalTrials.gov website, are they submitting
Medical researchers often presented the findings of their clinical trials in a different way on a federal government website than they did in the medical journals where their studies were ultimately published.
The trial registry ClinicalTrials.gov, which permits posting of trial results, includes results of some trials that have not been published in a peer-reviewed journal and in some cases includes more information than published trials.
A new analysis of 585 large, randomized clinical trials registered with ClinicalTrials.gov finds that 29 percent have not been published in scientific journals.
Almost one in three (29%) large clinical trials remain unpublished five years after completion.
Nearly nine out of ten clinicians carrying out biomedical research trials believe that trial data should be shared more easily, even though they do express some practical concerns.
Press releases and news stories reporting the results of randomized controlled trials often contain "spin"—specific reporting strategies (intentional or unintentional) emphasizing the beneficial effect of the experimental treatment—but such "spin" frequently comes from the abstract (summary) of the actual study published in a scientific journal, rather than being related to misinterpretation by the media.
In a study that investigates the challenges of disseminating clinical research findings in peer-reviewed biomedical journals, Yale School of Medicine researchers have found that fewer than half of a sample of trials primarily or partially funded by the National Institutes of Health (NIH) were published within 30 months of completing the clinical trial.