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Last updated on April 17, 2014 at 1:21 EDT

Latest trials Stories

2010-09-21 22:14:26

Press release from PLoS Medicine There are now 75 clinical trials and 11 systematic reviews of trials published every day, with no signs this pace is slowing. How will we ever cope?, ask Hilda Bastian, Paul Glasziou, and Sir Iain Chalmers in this week's PLoS Medicine, who also decry the continued poor quality of many of these studies. Analysing the history and growth of reviews of evidence, the authors recommend that we must now reduce unnecessary trials and prioritise truly systematic review...

2010-08-02 18:34:00

Comprehensive study of outcome reporting taps ClinicalTrials.gov BOSTON, Aug. 2 /PRNewswire-USNewswire/ -- When published results are systematically tracked for drug trials registered with ClinicalTrials.gov, those from industry-funded trials are the likeliest to be favorable to the drug in question, report researchers at Children's Hospital Boston. Publishing in the August 3 issue of the Annals of Internal Medicine, the researchers call for more public disclosure about clinical drug...

2010-07-12 12:55:32

Better design, reporting urged to ensure accurate results A Johns Hopkins review of nearly 150 randomized controlled trials on children "” all published in well-regarded medical journals "” reveals that 40 to 60 percent of the studies either failed to take steps to minimize risk for bias or to at least properly describe those measures. A report of the team's findings in the August issue of Pediatrics shows that experimental trials sponsored by pharmaceutical or medical-device...

2010-03-24 13:43:05

Research: The quality of reports of randomized trials in 2000 and 2006: Comparative study of articles indexed in PubMed New guidance to improve the reporting of trial findings is published simultaneously today (24 March 2010) by the BMJ and eight other leading journals around the world. Full and transparent reporting of trials is crucial to ensure that decisions about health care are based on the best available evidence. The guidance, known as the Consolidated Standards of Reporting Trials...

2010-01-11 16:26:39

Can we trust the results of research done on children? Flawed medical research could lead to children receiving treatment that either doesn't work or is harmful. Lisa Hartling, co-director for the University of Alberta's Alberta Research Centre for Health Evidence, looked at 163 North American clinical trials involving children by using a new tool that rates the risk of bias, meaning the benefits and safety of the treatments may have been exaggerated. She found that 96 per cent of the trials...

2009-08-19 10:17:14

A study by researchers at the University of Leicester has revealed new ways to spot whether medical research has hidden biases. Writing in the prestigious British Medical Journal, Santiago Moreno and his colleagues demonstrate how to spot "Ëœpublication bias' in the reporting of clinical trials which potentially form the basis of Government and NHS health policies. They also show what mathematical adjustments can be made to remove such unintended distortion of data.Health policies...

2009-07-08 07:19:04

Published clinical trials impact health care providers, consumers and policy-makers. New research shows many Chinese trials published as credible may not be fully accurate. Randomized Controlled Trials (RCTs) are one of the most powerful research tools for assessing new medical treatments. The Chinese Cochrane Centre at Sichuan University, and the China and Ottawa Hospital Research Institute investigated the clinical trials published between 1994 and 2005 in China. Trained investigators...

2009-06-10 06:09:00

JERUSALEM, June 10 /PRNewswire-FirstCall/ -- Oramed Pharmaceuticals, Inc. (OTCBB: ORMP.OB) (http://www.oramed.com), a developer of oral delivery systems, announced that Oramed was chosen to present at the 8th National Life Science & Technology Week ILSI-BIOMED Conference, Israel 2009. The presentation will be given by Mr. Nadav Kidron, President and CEO of Oramed, on Tuesday, June 16th during the BioPharma Session at 12:30 p.m. (local time) at the David Intercontinental Hotel in...

2009-02-10 16:40:29

U.S. researchers predict national electronic medical records could test drug efficacy on a par with randomized trials. However, researchers caution the need for at least 10 years of national data in the United States would be needed before electronic medical record data bases could be used to measure treatment efficacy. An appropriately configured electronic medical records data base could offer an invaluable tool, but we need to get to work now on how to configure it properly, study leader...

2009-01-26 08:42:23

The media are often blamed for only reporting on bad news. But in the world of medical news, the opposite may be true. New data suggest trials yielding positive treatment effects or striking findings were much more likely to be published in medical journals than trials with negative findings. Researchers are concerned this bias could be harmful to the general public. "Unless both positive and negative findings from clinical trials are made available, it is impossible to make a fair assessment...