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Latest Tricyclic antidepressant Stories

2012-08-21 02:26:59

SAN DIEGO, Aug. 21, 2012 /PRNewswire/ -- Millennium Laboratories, the leading research-based clinical diagnostic company dedicated to improving the lives of people suffering from pain, announced today that it has initiated a first-of-its-kind, large-scale prospective clinical outcomes study of its pharmacogenetic test. The study, which will encompass more than 30 practice sites nationally, is designed to evaluate the relationship between CYP genotype, as determined by Millennium...

2012-06-28 10:25:43

SAN DIEGO, June 28, 2012 /PRNewswire/ -- Millennium Laboratories, the leading research-based clinical diagnostic company dedicated to improving the lives of people suffering from pain, announced today the introduction of Millennium Pharmacogenetic Testing (PGT). Millennium PGT is saliva-based testing to detect genetic variations in enzymes associated with the metabolism of medications commonly prescribed to patients suffering from debilitating chronic pain and pain-related effects. This...

2012-04-05 21:01:19

African-Americans and Hispanics with major depressive disorder are less likely to get antidepressants than Caucasian patients, and Medicare and Medicaid patients are less likely to get the newest generation of antidepressants. Researchers from the University of Michigan School of Public Health examined data from 1993 to 2007 to try to understand the antidepressant prescribing patterns of physicians. They looked at two things: who received antidepressants, and what type of antidepressant...

2011-11-02 09:10:45

Among the most commonly used treatments for IBS, a targeted antibiotic was shown to be the safest in a new study by Cedars-Sinai researchers Among the most commonly used treatments for irritable bowel syndrome — which affects as many as 20 percent of the United States population — a targeted antibiotic was shown to be the safest in a new study by Cedars-Sinai researchers, based on an analysis of 26 large-scale clinical trials. The study, for presentation at the American...

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2011-08-04 06:45:00

Antidepressant use and the risk of adverse outcomes in older people: population-based cohort study New generation antidepressants, known as selective serotonin reuptake inhibitors (SSRIs) are associated with an increased risk of several severe adverse outcomes in older people compared with older tricyclic antidepressants (TCAs), finds a study published in the British Medical Journal on August 3. The authors say the risks and benefits of different antidepressants should be carefully evaluated...

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2011-04-26 06:35:00

A recent US study suggests that aspirin and other anti-inflammatory drugs, including ibuprofen and naproxen, may reduce the effectiveness of the most widely used anti-depressant medications -- selective serotonin reuptake inhibitors (SSRIs), reports AFP. The finding, published this week in the online issue of the Proceedings of the National Academy of Sciences, may explain why many depressed patients taking SSRIs do not respond to antidepressant treatment. Scientists at the Fisher Center...

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2010-09-29 14:44:24

Many researchers have studied the relationship between the increase in sales of new antidepressants in recent decades and a simultaneous decline in the suicide rate. In a study based on figures from the Nordic countries, researchers at the Norwegian Institute of Public Health found no evidence that increased sales of the new medicines could be linked to a lower suicide rate. The researchers also did not find any relationship between reduced sales of the older and more toxic antidepressants...

2010-02-05 13:47:30

Chemists at Oregon State University have discovered and synthesized a new compound that in laboratory and animal tests appears to be similar to, but may have advantages over one of the most important antidepressant medications in the world. A patent has been applied for on the compound, and findings on it published in the Journal of Medicinal Chemistry. Continued animal studies and eventually, human clinical trials will be necessary before the compound could be approved for human medical use,...

2009-05-07 11:38:00

STAMFORD, Conn., May 7 /PRNewswire/ -- RYZOLT(TM) (tramadol HCl extended-release tablets) is now available from Purdue Pharma L.P. for the management of moderate to moderately severe chronic pain in adults who require around-the-clock treatment of their pain for an extended period of time. (Photo: http://www.newscom.com/cgi-bin/prnh/20090507/NY13103) RYZOLT's active ingredient, tramadol, is a centrally-acting synthetic opioid analgesic that binds to the mu -opioid receptor and also...

2009-03-20 12:38:00

NEW YORK, March 20, 2009 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX) today announced that the U.S. Food and Drug Administration (FDA) has approved the Company's supplemental New Drug Application (sNDA) for Lexapro (escitalopram oxalate) for the acute and maintenance treatment of Major Depressive Disorder (MDD) in adolescents, 12 - 17 years of age. Lexapro is only the second antidepressant to be approved for the treatment of MDD in adolescents, a medical condition that...