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Latest Trifluoromethyl Stories

2011-08-16 23:10:07

New method simplifies the improvement of drugs and other compounds Scientists at The Scripps Research Institute have devised a much easier technique for performing a chemical modification used widely in the synthesis of drugs and other products. Known as "trifluoromethylation," the modification adds a CF3 molecule to the original compound, often making it more stable"”and, for a drug, keeping it in the body longer. With the new technique, chemists can perform this feat using a...

2010-06-25 14:54:18

New method could have a big impact on pharmaceutical business Some drugs may be more effective the longer they last inside the body. To prevent such drugs from being broken down too rapidly, pharmaceutical manufacturers often attach a fluorine-containing structure called a trifluoromethyl group. However, the processes now used require harsh reaction conditions or only work in a small number of cases, limiting their usefulness for synthesizing new drug candidates for testing. Now, MIT chemists...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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