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Latest Triple-negative breast cancer Stories

2011-06-02 12:39:00

Experimental drug may help reprogram tumor cells to respond to hormone therapy BALTIMORE, June 2, 2011 /PRNewswire-USNewswire/ -- A multicenter clinical trial led by a researcher at the University of Maryland Marlene and Stewart Greenebaum Cancer Center will evaluate a new approach to treat triple-negative breast cancer, an often-aggressive type of cancer that is more common among African-Americans and young women. The study will help researchers determine if an experimental drug,...

2011-04-04 19:45:14

Scientists from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are working on a series of genetic analyses that suggest the underlying differences among racial groups are present not just in tumors, but in normal tissue as well. Lisa Baumbach, Ph.D., associate research professor, and colleagues will present the full study results at the AACR 102nd Annual Meeting 2011, held here April 2-6. "Our group has been working for quite some time on the...

2011-04-01 01:11:31

Pilot study looking at stress, anxiety of aggressive breast cancer striking young minorities When an aggressive form of breast cancer strikes a young woman, what kind of stress, anxiety and other psychological and social challenges does she face? That question hasn't been answered in the published psychological cancer literature, but a new pilot study just launched is gathering data to change that, according to psychologist Georita M. Frierson at SMU. The two-year study will survey up to 60...

2011-03-22 15:25:20

Researchers led by Baylor College of Medicine have found a new way to tackle a difficult-to-treat form of breast cancer "“ a discovery that is being translated into human studies with currently approved FDA drugs. The new strategy begins with their discovery that a gene called PTPN12 plays a pivotal role in triple negative breast cancer, an aggressive form of the disease that accounts for approximately 20 percent of new cases of the disease and is resistant to common drugs such as...

2011-03-02 12:48:24

New findings published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, confirm the risk of breast cancer among women who are obese and not physically active, and suggests additional mechanisms beyond estrogen. Scientists from the Women's Health Initiative have found a relationship between obesity, physical activity and triple-negative breast cancer, a subtype of breast cancer characterized by a lack of estrogen, progesterone and...

2011-03-02 09:05:03

(Ivanhoe Newswire) "“ Obesity and inactiveness may increase the risk of triple-negative breast cancer, a subtype of breast cancer characterized by lack of estrogen, progesterone, and HER2 expression. Triple-negative breast cancers account for about 10 to 20 percent of all breast cancers and are associated with an extremely poor prognosis because of the lack of targeted drug therapies. "Breast cancer is not just one disease. It is a complex combination of many diseases," Amanda Phipps,...

2011-03-01 07:30:00

WALTHAM, Mass., March 1, 2011 /PRNewswire/ -- Syndax Pharmaceuticals, a clinical-stage epigenetics oncology company, announced the National Cancer Institute (NCI) will sponsor a multi-center phase 2 study of Syndax's lead product entinostat, a novel inhibitor of histone deacetylases (HDAC), and anastrozole, an aromatase inhibitor, in postmenopausal women with operable triple negative breast cancer to evaluate biomarkers and surrogates for response. The trial, to be conducted under a...

2011-02-25 12:41:00

SEATTLE, Feb. 25, 2011 /PRNewswire/ -- Full-term pregnancy has long been associated with a reduced risk of breast cancer, but a new study finds that the more times a woman gives birth, the higher her risk of "triple-negative" breast cancer, a relatively uncommon but particularly aggressive subtype of the disease. Conversely, women who never give birth have a 40 percent lower risk of such breast cancer, which has a poorer prognosis than other types of breast cancer and doesn't respond to...

2011-02-24 13:02:00

NEW HAVEN, Conn., Feb. 24, 2011 /PRNewswire/ -- Mira Dx announced today that it has licensed technology from Yale University based on the acceptance of a pivotal breast cancer study in the January issue of the journal Cell Cycle. While numerous BRCA1 coding sequence mutations are associated with breast cancer risk, such mutations in BRCA1 account for less than 5% of breast cancer risk. The research identified microRNA disrupting variants in and around BRCA1 that are polymorphic in breast...

2011-02-07 14:00:00

GLENWILLOW, Ohio, Feb. 7, 2011 /PRNewswire/ -- Dots, LLC announced today that it will donate $91,086 to Susan G. Komen for the Cure® to help fund ground-breaking research and life-saving community outreach projects through the "Girlfriends Giving Back" partnership program. (Photo: http://photos.prnewswire.com/prnh/20110207/CL43584 ) (Logo: http://photos.prnewswire.com/prnh/20081202/CLTU086LOGO ) Only in its second year, the Dots "Girlfriends Giving Back" program...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.