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Kicking Cocaine Addiction With A One-Two Punch
2012-08-09 10:56:41

Connie K. Ho for redOrbit.com — Your Universe Online Researchers from Scripps Research Institute recently revealed that a two-drug combination could possibly help those battling cocaine addiction. The combination made up of naltrexone and buprenoprine, two existing pharmaceutical drugs, is a therapy that would help reduce individuals´ want for cocaine and also lessen their feelings of withdrawal. Scientists believed that the therapy is a step forward as there are currently no...

2012-07-30 06:27:03

(Ivanhoe Newswire) — Cocaine is presently the most abused major stimulant drug in America. It has also become the drug most frequently involved in emergency department visits. Now researchers are saying the solution to the addiction problem could be in the form of enzymes. Researchers from the University of Kentucky have designed and discovered a series of highly efficient enzymes that effectively metabolize cocaine. These high-activity cocaine-metabolizing enzymes could potentially...

2012-07-27 10:59:49

Researchers from the University of Kentucky have designed and discovered a series of highly efficient enzymes that effectively metabolize cocaine. These high-activity cocaine-metabolizing enzymes could potentially prevent cocaine from producing physiological effects, and could aid in the treatment of drug dependency. The results of this study by Chang-Guo Zhan et al are published in the journal PLOS Computational Biology. The effectiveness of the enzymes' work was evaluated through...

2012-06-18 23:31:12

A single-dose vaccine capable of providing immunity against the effects of cocaine offers a novel and groundbreaking strategy for treating cocaine addiction is described in an article published Instant Online in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc. (http://www.liebertpub.com) The article is available free online at the Human Gene Therapy website (http://www.liebertpub.com/hum). "This is a very novel approach for addressing the huge medical problem of...

2012-06-06 21:42:30

The discovery of the first enzyme in the pathway sheds new light on the evolution of alkaloid formation Humans encounter alkaloids every day Alkaloids constitute a very large group of natural nitrogen-containing compounds with diverse effects on the human organism. A large variety of plant-produced alkaloids have strong pharmacological effects, and are used as toxins, stimulants, pharmaceuticals or recreational drugs, including caffeine, nicotine, morphine, quinine, strychnine, atropine...

Chronic Cocaine Use Triggers Changes In Brain's Neuron Structure
2012-05-09 14:26:44

Chronic exposure to cocaine reduces the expression of a protein known to regulate brain plasticity, according to new, in vivo research on the molecular basis of cocaine addiction. That reduction drives structural changes in the brain, which produce greater sensitivity to the rewarding effects of cocaine. The finding suggests a potential new target for development of a treatment for cocaine addiction. It was published last month in Nature Neuroscience by researchers at the University at...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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