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Chronic exposure to cocaine reduces the expression of a protein known to regulate brain plasticity, according to new, in vivo research on the molecular basis of cocaine addiction.
The United Nations Office on Drugs and Crime estimates that cocaine is used by up to 21 million individuals worldwide, with approximately 1 per cent of these individuals becoming dependent.
Found in more than 400,000 emergency room visits and related to 5,000 overdose deaths a year in the United States, cocaine is a highly dangerous drug that can lead to death.
When first exposed to cocaine, the adolescent brain launches a strong defensive reaction designed to minimize the drug's effects, Yale and other scientists have found.
Research published by Cell Press in the January 12 issue of the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine.
When a research team asked cocaine addicts to choose, hypothetically, between money now or cocaine of greater value later, "preference was almost exclusively for the money now," said Warren K., Bickel, professor in the Virginia Tech Carilion Research Institute, director of the Advanced Recovery Research Center, and professor of psychology in the College of Science at Virginia Tech.
New discoveries by researchers at the University of Wisconsin-Milwaukee (UWM) offer potential for development of a first-ever pharmacological treatment for cocaine addiction.
JERUSALEM, June 23, 2011 /PRNewswire/ -- IDenta Corp. (PINKSHEETS: IDTA) CEO Yaacov Shoham today announced that the company's test kits were recently used by Argentinian law enforcement officials to identify and confirm a large shipment of illegal cocaine from Argentina.
Researchers at the University of Cambridge have identified abnormal brain structures in the frontal lobe of cocaine users' brains which are linked to their compulsive cocaine-using behavior.
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