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Latest TRPV1 Stories

2014-05-13 08:31:28

SAN DIEGO, May 13, 2014 /PRNewswire/ -- Sorrento Therapeutics, Inc. (NASDAQ: SRNE; Sorrento) a late-stage clinical oncology company developing new treatments for cancer and its associated pain, today announced that the U.S. Office of Orphan Products Development at the Food and Drug Administration (FDA) has approved the transfer of sponsorship of the Orphan Drug Designation for intrathecal resiniferatoxin (RTX) in the treatment of intractable pain in end-stage disease from the...

2014-02-06 08:28:24

SAN DIEGO, Feb. 6, 2014 /PRNewswire/ -- Sorrento Therapeutics, Inc. (NASDAQ: SRNE; Sorrento), a late-stage clinical oncology company developing new treatments for cancer and associated pain, announced today that Dr. Henry Ji, President and Chief Executive Officer of Sorrento, will present at the 16(th) Annual BIO CEO & Investor Conference. Hosted by the Biotechnology Industry Organization (BIO), the 16th Annual BIO CEO & Investor Conference will take place February 10 -11 at...

2013-10-30 11:07:26

A crucial component of wound healing in many animals, including humans, is the migration of nearby skin cells toward the center of the wound. These cells fill the wound in and help prevent infection while new skin cells regenerate. How do these neighboring skin cells know which way to migrate? What directional cues are they receiving from the wound site? A new paper by Mark Messerli and David Graham of the MBL’s Eugene Bell Center for Regenerative Biology and Tissue Engineering clarifies...

The Itch Molecule
2013-05-24 08:20:02

April Flowers for redOrbit.com - Your Universe Online Using mouse models, researchers at the National Institutes of Health (NIH) have discovered a small molecule that is released in the spinal cord that triggers a process later experienced in the brain as the sensation of itch. The results of this study were published in a recent issue of Science. The molecule, natriuretic polypeptide b (Nppb), selectively plugs into a specific nerve cell in the spinal cord. This nerve cell sends...

Study Finds Hot And Cold Senses Interact
2013-04-09 10:20:59

University of North Carolina Health Care A study from the University of North Carolina School of Medicine offers new insights into how the nervous system processes hot and cold temperatures. The research led by neuroscientist Mark J. Zylka, PhD, associate professor of cell biology and physiology, found an interaction between the neural circuits that detect hot and cold stimuli: cold perception is enhanced when nerve circuitry for heat is inactivated. "This discovery has implications for...

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2011-08-04 05:50:00

Researchers have discovered the genetic pathway that allows vampire bats to identify the "hot spots" in their prey that are most likely to contain ample amounts of blood, according to a new study published Wednesday. Biologists have long known that bats can detect blood vessels from up to 8 inches away, but it was unclear how they did it fast enough to strike and retreat without alerting their prey. Researchers at the University of California, San Francisco and Instituto Venezolano de...

2011-06-16 07:00:00

SAN MATEO, Calif., June 16, 2011 /PRNewswire/ -- NeurogesX, Inc. (Nasdaq: NGSX), a biopharmaceutical company focused on developing and commercializing novel pain management therapies, today announced the completion of patient enrollment in its Phase 2 clinical study of NGX-1998, a topical liquid formulation of high-concentration capsaicin, in patients with postherpetic neuralgia (PHN). NGX-1998 is being developed to provide safety, efficacy and tolerability that is at least comparable to...

2011-04-28 07:00:00

SAN MATEO, Calif., April 28, 2011 /PRNewswire/ -- NeurogesX, Inc. (Nasdaq: NGSX), a biopharmaceutical company focused on developing and commercializing novel pain management therapies, today announced that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for its patent entitled, "Methods and Compositions for Administration of TRPV1 Agonists." The allowed claims include method of use, formulation and system claims. The patent scheduled to issue from this...

2011-04-27 13:24:11

Research at Children's National uncovers an unknown side effect of a promising drug for acute chronic pain Pain researchers from the Sheikh Zayed Institute for Pediatric Surgical Innovation at Children's National Medical Center have discovered that resiniferatoxin, a drug that has shown early promise as an option for chronic, severe pain sufferers, may decrease the body's ability to fight off bacterial infections, particularly sepsis. The study, which appears in the May 1 edition of the...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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