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2009-03-30 12:55:08

In China, the incidence of liver cirrhosis is still high. Liver cirrhosis results from fibrosis. If treated properly at fibrosis stage, cirrhosis can be prevented. However, no effective antifibrosis drugs are available at present. Several lines of evidences suggest that oxidative stress plays an important role in the etiopathogenesis of hepatic fibrosis. Melatonin can protect cells, tissues, and organs against oxidative damage induced by a variety of free-radical-generating agents and...

2009-03-06 07:00:00

NEW YORK and SAN DIEGO, March 6, 2009 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX) and Cypress Bioscience, Inc. (Nasdaq: CYPB) announced today that they expect to ship Savella(TM) (milnacipran HCl), a selective serotonin and norepinephrine reuptake inhibitor for the management of fibromyalgia, to wholesalers and pharmacies by mid 2009. Savella was approved by the U. S. Food and Drug Administration (FDA) on January 14, 2009 and was originally expected to be available in...

2009-03-03 09:00:00

Cherries Offer Natural Source of Antioxidant Melatonin LANSING, Mich., March 3 /PRNewswire/ -- Setting the clocks forward this spring can have the unfortunate side effect of disrupting your body's clock. In fact, research indicates that losing even one hour of sleep may affect us for days or even weeks.(i) Experts recommend the antioxidant melatonin as one way to help regulate the body's sleep-wake cycle. Produced naturally by the body in small amounts, melatonin plays a role in inducing...

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2009-02-26 09:20:28

It takes weeks or months for the effect of most antidepressants to kick in, time that can feel like an eternity to those who need the drugs the most. But new research suggests that a protein called p11, previously shown to play a role in a person's susceptibility to depression, activates a serotonin receptor in the brain known for producing a rapid antidepressant response. If scientists could develop drugs to target this receptor, they might produce an effect in as little as two days. The...

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2009-02-25 11:34:57

Scientists in Britain reported on Wednesday, whether you are pessimistic or optimistic may depend on a single, hormone-delivery gene. In other words, some people are likely hard-wired for happiness, while others are genetically geared towards sadness, according to a study published in Britain's Proceedings of the Royal Society B. The gene known as 5-HTTLPR plays a key role in determining how the neurotransmitter serotonin functions within the brain. Serotonin transmits chemical messages...

2009-02-24 11:59:00

PARIS, January 24 /PRNewswire/ -- The European Commission has granted marketing authorisation for Servier's Valdoxan(R) /Thymanax(R) (agomelatine), the first melatonergic antidepressant for the treatment of adult patients with major depressive episodes. "There is still great scope for improved therapies to treat the devastating effects of depression," said Professor Goodwin from Warneford Hospital, Oxford, United Kingdom. "Valdoxan is an innovative, new approach to the management of...

2009-02-13 10:08:21

A hallucinogenic compound found in a plant indigenous to South America and used in shamanic rituals regulates a mysterious protein that is abundant throughout the body, University of Wisconsin-Madison researchers have discovered.The finding, reported in the Feb. 13 issue of Science, may ultimately have implications for treating drug abuse and/or depression. Many more experiments will be needed, the researchers say.Scientists have been searching for years for naturally occurring compounds that...

2008-11-14 12:00:05

Lexicon Pharmaceuticals, a biopharmaceutical company, has successfully completed a second Phase I clinical trial of LX1032, an orally-delivered small molecule drug candidate for managing gastrointestinal symptoms associated with carcinoid syndrome. Based on the results from this study, Lexicon is planning to initiate a Phase II study in patients with carcinoid syndrome. LX1032 will be Lexicon's third drug candidate to progress to Phase II clinical trials. Clinical development of LX1032 is...

2008-11-13 06:00:36

Natrol, Inc., a premier marketer, manufacturer, and distributor of nationally branded nutritional products, knows that the hectic holidays can cause consumers stress due to mood swings and stress, unhealthy eating, obligations, time constraints, and general lack of exercise and sleep. This year's holiday season may be more stressful for many Americans due to the current business and economic climate negatively affecting finances. These factors may contribute to an unhealthy body and...

2008-10-16 12:00:25

Recent worrisome events and news has caused stress, poor mood, and even fear for many Americans. Today's business, economic, and world crises have added to already complicated American lives, possibly pushing even the most serene people over the edge, especially for those most affected by the latest events (such as people in banking, finance, and real estate who've seen their jobs diminish or disappear). The American Psychological Association's (APA) annual Stress in America survey --...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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