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Latest Tuberculosis treatment Stories

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2010-03-04 14:15:00

By going 'back to the drawing board,' 2 teams advance on answers to TB epidemic When people get exposed to the mycobacterium responsible for tuberculosis (TB), some will become sick with a disease that is a major cause of mortality around the world while others simply don't. Now, researchers reporting in the March 5th issue of the journal Cell, a Cell Press publication, can point to one important reason for this variation in susceptibility or resistance: genetic differences among individuals...

2010-03-04 07:00:00

MIAMI, March 4 /PRNewswire/ -- Data evaluating the efficacy and safety of STELARA(TM) (ustekinumab) and REMICADE® (infliximab) in patients with plaque psoriasis who had an inadequate response to Enbrel® (etanercept) will be presented at the 68th Annual Meeting of the American Academy of Dermatology (AAD) in Miami, Fla., from March 5-9, 2010. Cumulative safety data for STELARA(TM) (up to 18 months) based on pooled analyses of one Phase 2 and two Phase 3...

2010-02-16 07:53:58

Indiana University School of Medicine researchers have identified a mechanism used by the tuberculosis bacterium to evade the body's immune system and have identified a compound that blocks the bacterium's ability to survive in the host, which could lead to new drugs to treat tuberculosis. Zhong-Yin Zhang, Ph.D., Robert A. Harris Professor and chairman of the Department of Biochemistry and Molecular Biology, and his colleagues revealed the biochemical processes that TB bacteria employ to...

2009-12-23 14:03:16

Scientists have identified a strain of antibiotic-resistant tuberculosis that thrives in the presence of rifampin, a front-line drug in the treatment of tuberculosis. The bacterium was identified in a patient in China and is described in a study by researchers at the Johns Hopkins Bloomberg School of Public Health, Chongqing Pulmonary Hospital, Lanzhou University and Fudan University. The researchers determined that the bacteria grew poorly in the absence of the antibiotic rifampin and better...

2009-11-16 10:45:00

LEUVEN, Belgium and LUND, Sweden, November 16 /PRNewswire-FirstCall/ -- ThromboGenics NV (Euronext Brussels: THR) and BioInvent International AB (OMXS: BINV) today announced positive results from a Phase I trial of their novel anti-cancer monoclonal antibody TB-403 in patients with advanced solid tumours. The results were presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston, U.S. TB-403 was well tolerated with no reported dose...

2009-10-09 10:35:00

New optical technique provides easy way to detect TB bacteria in fluids Two billion people worldwide carry the pathogen that causes tuberculosis (TB), and most of them do not even know they are infected. This is because some 90 percent of people with TB have "latent" infections. They have no symptoms, they can't spread the disease to others and the bug remains dormant in their lungs -- often for years. Detecting latent TB infections is an important public health problem because those 10...

2009-09-29 08:00:00

SEATTLE, Sept. 29 /PRNewswire-FirstCall/ -- On behalf of The Lilly TB Drug Discovery Initiative, the Infectious Disease Research Institute (IDRI) today signed a Memorandum of Understanding (MOU) with Academia Sinica, a research institution based in Taiwan, to collaborate in target-based screening for the discovery of new tuberculosis (TB) drugs. The Lilly TB Drug Discovery Initiative's most important goal is filling the pipeline for faster, future TB drug development. In recent...

2009-09-17 14:07:26

U.S. researchers say they have identified compounds that can inhibit tuberculosis bacteria without harming human cells. The scientists, led by researchers at the Weill Cornell Medical College, said their findings include structural studies of how the inhibitor molecules interact with TB bacterial proteins and could lead to the design of new anti-TB drugs. We believe these findings represent a new approach for developing antibiotics in the fight against TB, Professor Carl Nathan, senior author...

2009-09-15 07:55:05

International guidelines for treating tuberculosis are due for specific improvements, according to two research papers published this week in the open access journal PLoS Medicine. Public health programs in many countries adhere to World Health Organization (WHO) guidelines as the authoritative recommendations for treating tuberculosis (TB). But do these guidelines reflect the best available evidence? To answer this question, Dick Menzies of McGill University in Montreal and colleagues...

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2009-08-07 12:45:00

Children with type 1 diabetes are at an increased risk of developing tuberculosis, according to a new report.Writing in the International Journal of Tuberculosis and Lung Diseases, Dr. E. A. Webb, from the Desmond Tutu Tuberculosis Center, Cape Town, South Africa, and colleagues found that almost one in three children with type 1 diabetes tested positive for TB, placing them and others around them at risk of being infected.TB is present in billions of people worldwide, but it usually does not...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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