Latest Tuberculosis treatment Stories

2009-09-15 07:55:05

International guidelines for treating tuberculosis are due for specific improvements, according to two research papers published this week in the open access journal PLoS Medicine. Public health programs in many countries adhere to World Health Organization (WHO) guidelines as the authoritative recommendations for treating tuberculosis (TB). But do these guidelines reflect the best available evidence? To answer this question, Dick Menzies of McGill University in Montreal and colleagues...

2009-08-07 12:45:00

Children with type 1 diabetes are at an increased risk of developing tuberculosis, according to a new report.Writing in the International Journal of Tuberculosis and Lung Diseases, Dr. E. A. Webb, from the Desmond Tutu Tuberculosis Center, Cape Town, South Africa, and colleagues found that almost one in three children with type 1 diabetes tested positive for TB, placing them and others around them at risk of being infected.TB is present in billions of people worldwide, but it usually does not...

2009-07-30 12:35:00

The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques,UT Southwestern Medical Center researchers said. The finding, reported online and in the August edition of Antimicrobial Agents and Chemotherapy, is particularly important for those living in societies plagued by obesity, said Dr. Tawanda Gumbo, associate professor of internal medicine at UT Southwestern and the study's lead author."What really drives...

2009-07-23 08:25:00

Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.A report on the...

2009-07-06 08:31:50

Extreme drug-resistant tuberculosis (TB) kills about two million people each year; a number researchers are trying to lower with new medicines for TB. Currently prescribed to treat Parkinson's disease, entacapone and tolcapone may also be able to treat severe TB cases. The drugs currently used to treat TB are highly toxic and of a completely different chemical structure than the two new drugs.  "Here we have drugs that are known to be safe with suitable binding properties which can be...

2009-07-03 09:55:00

Drugs used to care for Parkinson's disease might be a new way to halt the increase of drug-resistant forms of tuberculosis, U.S. researchers announced on Thursday.They stated that both computer models and lab experiments found that the drugs tolcapone, or Tasmar, made by Valeant Pharmaceuticals, and entacapone, or Comtan, made by Novartis AG have the possibility to fight multiple-drug-resistant strains of TB.Computer programs forecasted that the chemically comparable drugs should throw off...

2009-06-30 13:28:35

Tuberculosis (TB) is a difficult infection to treat and requires six months of multiple antibiotics to cure it. To combat the TB pandemic, a shorter and simpler drug treatment would be a huge advance since most TB occurs in resource-limited settings with poor public health infrastructures.Testing whether two simple clinical measurements might help identify which TB patients could benefit from shorter treatment, researchers at Case Western Reserve University and University Hospitals (UH) Case...

2009-06-17 08:15:00

SEATTLE, June 17 /PRNewswire/ -- When: Wednesday, June 17, 2009, 10:30am Eastern (9:30am Central; 8:30am Mountain; 7:30am Pacific) Dial-in: 1-877-879-6184 (toll-free) 1-719-325-4759 (local access) Conference Title: TB Alliance/Tibotec Briefing Participant passcode: 2895940 Where: Pacific Health Summit Bell Harbor International Conference Center Pacific Board Room Seattle,...

2009-06-03 16:00:00

Clinical Activity Of TMC207 shows ATP-Synthase is a Viable Target for treatment of TB MECHELEN, Belgium, June 3 /PRNewswire/ -- Interim results from an ongoing phase 2, randomized, placebo-controlled trial of the investigational drug TMC207 for the treatment of multidrug-resistant tuberculosis (MDR-TB) were published in the New England Journal of Medicine today. TMC207 is being developed by Tibotec BVBA. The data show that the addition of TMC207 for eight weeks to a 5-drug background...

2009-05-20 07:20:00

New estimates of the likelihood that a latent case of tuberculosis (TB) will become active have resulted in a roughly 50 percent increase over previous estimates of the number of people needed to be screened (NNS) to prevent an active infection, limiting the cost effectiveness of screening in many Center for Disease Control and Prevention (CDC)-defined risk groups, according to an analysis conducted by experts in the epidemiology of the disease. The research will be presented at the American...

Word of the Day
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.