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Latest tuberculosis Stories

2012-10-23 20:48:07

A study led by The University of Manchester has demonstrated that new technology that can analyze millions of gene sequences in a matter of seconds is an effective way to quickly and accurately identify diseases in skeletons. Professor Terry Brown, working in partnership with Professor Charlotte Roberts from Durham University, used a next generation sequencing approach, including hybridization capture technology, to identify tuberculosis genes in a 19th century female skeleton found in a...

2012-10-23 20:33:07

Lead scientist Professor Simon Cutting, from the School of Biological Sciences at Royal Holloway, has developed the jabs through the use of probiotic spores. He carried out fundamental studies into the biology of the bacterium Bacillus subtilis which attracted the attention of microbiologists due to its ability to form spores that can last millions of years before germinating under the appropriate environmental conditions. Professor Cutting says: "The mechanisms by which this process...

2012-10-09 23:20:19

Phase IIb Proof of Concept Trial Planned for Kenya, India and South Africa ROCKVILLE, Md., Oct. 10, 2012 /PRNewswire-USNewswire/ -- Aeras announces that it has signed an agreement with GlaxoSmithKline Vaccines, S.A. (GSK) to jointly advance the clinical development of an investigational tuberculosis (TB) vaccine containing GSK's proprietary M72 antigen and AS01(E)(*) adjuvant. This novel research and resource-sharing agreement between the largest non-profit TB vaccine biotech and one...

2012-09-27 10:10:56

Results from an observational study evaluating a new anti-TB drug have found that the treatment can improve outcomes and reduce mortality among patients with both MDR-TB and XDR-TB. The research, published online ahead of print today (27 September 2012) in the European Respiratory Journal, suggests a drug called delamanid could have a public health benefit for MDR-TB and also for XDR-TB, as few effective treatment options are currently available. Over the past two decades,...

2012-09-20 02:28:47

PARIS and NEW YORK, Sept. 20, 2012 /PRNewswire/ -- Sanofi (EURONEXT: SAN and NYSE: SNY) and the Global Alliance for TB Drug Development (TB Alliance) announced today a new research collaboration agreement to accelerate the discovery and development of novel compounds against tuberculosis (TB), a deadly infectious disease that resulted in almost 1.5 million deaths worldwide(1) in 2010. (Logo: http://photos.prnewswire.com/prnh/20110616/NY20158LOGO ) Under the agreement, Sanofi and...

Drug-resistant Tuberculosis Killed By Old Pain Drug
2012-09-11 09:08:37

April Flowers for redOrbit.com - Your Universe Online Researchers at Weill Cornell Medical College have found that an off-patent anti-inflammatory drug that costs about two cents for a daily dose can also kill both replicating and non-replicating drug-resistant tuberculosis in the laboratory. Few currently approved TB drugs can do this, and resistance to those is spreading. Reported in the Proceedings of the National Academy of Sciences, the study points to a potential new therapy for...

2012-09-11 02:28:40

MONMOUTH JUNCTION, N.J., Sept. 11, 2012 /PRNewswire/ -- Insmed Incorporated (NASDAQ: INSM), a biopharmaceutical company focused on developing novel inhalation therapeutics for patients suffering from serious orphan lung diseases, today announced the appointment of Will Lewis as President and Chief Executive Officer, effective immediately. Mr. Lewis has also been appointed to the Company's Board of Directors. He succeeds Tim Whitten, who has resigned as President and Chief Executive Officer...

2012-09-10 23:04:28

Critical Path Institute and CDISC (Clinical Data Interchange Standards Consortium) announce the availability of a breakthrough tool to help combat tuberculosis (TB)–a persistent disease resulting in 1.7 million deaths globally each year. Tucson, AZ (PRWEB) September 10, 2012 Critical Path Institute and CDISC (Clinical Data Interchange Standards Consortium) announce the availability of a breakthrough tool to help combat tuberculosis (TB)–a persistent disease resulting in 1.7...

2012-09-06 12:48:22

Provocative NEJM essay calls for redoubling of efforts Each year, nearly 2 million people die from tuberculosis — a treatable disease that has been brought under control in the United States, but continues to ravage other parts of the world. This health inequity should prompt a complete rethinking of the way tuberculosis is fought on a global level, argue Salmaan Keshavjee, MD, PhD, and Paul Farmer, MD, PhD, from Brigham and Women's Hospital (BWH). Their argument appears in an essay...

2012-09-05 02:31:43

RARITAN, N.J., Sept. 5, 2012 /PRNewswire/ -- Janssen Research & Development, LLC (Janssen) announced today that the U.S. Food and Drug Administration (FDA) has granted Priority Review to the New Drug Application (NDA) for bedaquiline (TMC207) to treat pulmonary, multi-drug resistant tuberculosis (MDR-TB) in adults as part of combination therapy. The FDA grants priority review to medicines that may offer major advances in care or provide a treatment option where no adequate therapy...


Latest tuberculosis Reference Libraries

72_0ab04c9452ae9b3c6ae51f6deb1bcc35
2011-04-25 16:19:14

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Robert Koch first discovered it in 1882 and that it had an unusual, waxy coating on the cell surface which makes them impossible to Gram stain. M. tuberculosis is highly aerobic and requires high levels of oxygen. It generally infects the respiratory system of mammals. Tuberculin skin test, acid-fast stain, and chest radiographs are the most...

45_255d6ba67dfe6f32b9c7c31f338bf912
2011-04-18 22:11:24

Mycobacterium bovis is a slow-growing, aerobic bacterium and the causative agent of tuberculosis in cattle. Similar to M. tuberculosis, M. bovis can jump the species barrier and cause tuberculosis in humans. It is estimated that M. bovis was responsible for more losses among farm animals than all other diseases combined in the first half of the 20th century. Infection happens after bacterium is ingested. It is generally transmitted to humans via infected milk. Actual human infections are...

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