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Latest Tumor antigen Stories

2009-06-18 11:21:02

TAU research uses the Ras protein to fight its own malign effects Oncogenes are genes that when mutated or expressed in high concentrations can cause normal cells to become cancerous. Now research from Tel Aviv University is demonstrating that Ras, one of the first oncogenes discovered, has the power to heal as well as harm. Ph.D. student Oded Rechavi and his fellow researchers at Tel Aviv University's Department of Neurobiology have found that Ras has the ability to transfer from cancer...

2009-06-04 15:30:00

RARITAN, N.J., June 4 /PRNewswire/ -- Ortho Biotech Oncology Research & Development, a unit of Centocor Research & Development, Inc., today announced that it has entered into a five-year Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute (NCI), with Steven A. Rosenberg, M.D., Ph.D., chief, Surgery Branch, serving as the NCI principal investigator, to research and develop novel cell therapy technologies as potential treatments for a variety of...

2009-01-13 09:48:29

New approaches to gene therapy have been found that help eradicate brain tumors and boost the power of the immune system. Researchers at Cedars-Sinai Medical Center in Los Angeles found that HMGB1, a protein released from deteriorating tumor cells, activates dendritic cells and stimulates anti-tumor responses by attaching to an inflammatory receptor known as toll-like receptor 2, TLR2. Evidence shows that toll receptors are responsible for not only recognizing bacterial components, but also...

2009-01-12 19:00:00

U.S. researchers say they used the human genetic code to attract key immune cells into the brain, where they then recognized and attacked tumor cells. The Cedars-Sinai Medical Center researchers in Los Angeles discovered that a protein known as high-mobility group box 1, or HMGB1, released from dying tumor cells activates key immune cells called dendritic cells and stimulates a strong and effective anti-tumor immune response. But the number of dendritic cells in the brain is very small,...

2008-10-22 12:00:20

ERYtech Pharma, a French biotechnology company, will present very promising results from its original approach on antitumor vaccination at the 6th International Cancer Vaccine Symposium to be held in New York from October 28-30, 2008. These results, obtained from animal studies confirm that the Vaccin'ERY(TM) system is efficient. This technology, patented by ERYtech Pharma, is very unique. It consists in using tumor antigens loaded red blood cells to specifically target and activate...

2008-10-10 09:00:52

ImmunoCellular Therapeutics, a biotechnology company, has filed a provisional US patent application relating to its vaccine technology targeting cancer stem cells. The vaccine technology is exclusively licensed from Cedars-Sinai Medical Center. The patent claims are broad and include compositions of peptides for cancer immunotherapy as well as methods for inducing immune responses against tumor antigens in cancer patients. The vaccine being developed by ImmunoCellular Therapeutics (IMUC)...

2008-09-23 06:00:32

ImmuneRegen BioSciences, Inc., a wholly owned subsidiary of IR BioSciences Holdings, Inc. (OTCBB: IRBS), today announces a collaborative relationship with the University of North Carolina at Charlotte to evaluate ImmuneRegen's Viprovex as a possible cancer-vaccine adjuvant. Adjuvants are agents that stimulate and, subsequently, augment the immune system's response to a foreign antigen. The studies will be under the direction of Pinku Mukherjee, Ph.D., an accomplished cellular immunologist...

2008-06-25 09:02:27

By Akins, Elizabeth J Dubey, Purnima Cell-mediated therapy (immunotherapy) for the treatment of cancer is an active area of investigation in animal models and clinical trials. Despite many advances, objective responses to immunotherapy are observed in a small number of cases, for certain tumor types. To better understand differences in outcomes, it is critical to develop assays for tracking effector cell localization and function in situ. The fairly recent use of molecular imaging...

2008-06-18 18:00:00

SEATTLE, June 18 /PRNewswire/ -- Researchers describe the first successful use of a human patient's cloned infection-fighting T cells as the sole therapy to put an advanced solid-tumor cancer into long-term remission. A team led by Cassian Yee, M.D., an associate member of the Clinical Research Division at Fred Hutchinson Cancer Research Center, reports these findings in the June 19 issue of the New England Journal of Medicine. Yee and colleagues removed CD4+ T cells, a type of white...

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2008-04-21 10:25:00

A new fundamental mechanism of how tumor cells communicate has just been discovered by the team of Dr. Janusz Rak at the Research Institute of the McGill University Health Centre (MUHC) in collaboration with Dr Guha from the University of Toronto. The cancer cells are able to communicate with their more healthy counter-parts by releasing vesicles. These bubble-like structures contain cancer-causing (oncogenic) proteins that can trigger specific mechanisms when they merge into non or...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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