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Latest Tumor hypoxia Stories

2014-10-17 23:08:13

NuvOx Pharma, a biotechnology company based in Tucson, Arizona, has received a $1Million grant from the National Cancer Institute (NCI) “Nanoparticle-based Sensitizer for Radiation Therapy of Glioblastoma, (NCI Phase II SBIR, R44CA144817 - 02A1)". Tucson, AZ (PRWEB) October 17, 2014 NuvOx Pharma, a biotechnology company based in Tucson, Arizona, has received a $1Million grant from the National Cancer Institute (NCI) “Nanoparticle-based Sensitizer for Radiation Therapy of...

2014-10-09 12:29:10

- $5.8 million award will help advance the development of oxygen-carrying therapeutics for cancer - SAN CARLOS, Calif., Oct. 9, 2014 /PRNewswire/ -- Omniox, Inc., an IND-stage biopharmaceutical company developing therapeutics for hypoxic diseases, announced today that the company has been granted a Translation Fund Award from the Wellcome Trust. The $5.8 million award will advance development of Omniox's lead product, OMX-4.80, for the treatment of hypoxic cancers including...

2013-12-11 12:57:14

They have discovered how the anti-tumor activity of immune cells can be restored The Leuven-based VIB researchers have revealed a mechanism that explains why the anti-tumor activity of specific immune cells called macrophages is suppressed during tumor growth. They have also demonstrated that blocking the protein Nrp1 can restore this anti-tumor immune response. This is a first. Nrp1 may provide an important hub for the development of new therapies against cancer. Max Mazzone: "For many...

2013-01-10 14:00:27

By harnessing the very qualities that make sickle cell disease a lethal blood disorder, a research team led by Duke Medicine and Jenomic, a private cancer research company in Carmel, Calif., has developed a way to deploy the misshapen red blood cells to fight cancer tumors. Reporting in the Jan. 9, 2013, edition of the on-line journal, PLOS ONE, the researchers describe a process of exploiting sickle-shaped red blood cells to selectively target oxygen deprived cancer tumors in mice and...

2013-01-10 13:58:00

Sickle-shaped red blood cells target and destroy tumor cells and blood vessels The genetic mutation that causes sickle cell anemia also turns red blood cells into potent tumor killers and may offer a new way to treat some cancers that are resistant to existing treatments, according to research published January 9 in the open access journal PLOS ONE by David S. Terman of Jenomic Research Institute and colleagues from Duke University and other institutions. The mutation that causes sickle...

2012-09-13 13:34:51

It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, is in fact linked with more aggressive tumor behavior and poorer prognosis. It´s as if rather than succumbing to gently hypoxic conditions, the lack of oxygen commonly created as a tumor outgrows its blood supply signals a tumor to grow and metastasize in search of new oxygen sources — for...

2011-08-16 12:19:04

Tumors that do not respond to chemotherapy are the target of a cancer therapy that prevents the function of two enzymes in mouse tumor cells, according to Pennsylvania medical researchers. "We've known for well over a decade that when tumors become hypoxic they become resistant to chemotherapy and radiotherapy," said Wafik S. El-Deiry, M.D. Ph.D., American Cancer Society Research Professor, Rose Dunlap Professor and chief of hematology/oncology, Penn State College of Medicine. "This is a huge...

2011-05-24 07:00:00

PALO ALTO, Calif. and AUCKLAND, New Zealand, May 24, 2011 /PRNewswire/ -- Centella Therapeutics, Inc., a subsidiary of Varian Medical Systems, Inc. (NYSE: VAR), and Auckland UniServices Ltd. of Auckland, New Zealand, today announced that they have entered into a licensing agreement granting Centella exclusive rights to CEN-209, a novel investigational drug designed to enhance the effectiveness of radiotherapy and chemotherapy when treating solid tumors that are hypoxic--or...


Word of the Day
negawatt
  • A unit of saved energy.
Coined by Amory Lovins, chairman of the Rocky Mountain Institute as a contraction of negative watt on the model of similar compounds like megawatt.