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Latest Tumor necrosis factor-alpha Stories

2011-09-08 09:46:14

Malignancies associated with tumor necrosis factor inhibitors in registries and prospective observational studies: a systematic review and meta analysis Biological agents used to treat rheumatoid arthritis seem to be associated with an increased risk of skin cancer, indicates a systematic review of published research in the Annals of the Rheumatic Diseases. Inflammatory arthritis has been linked to an increased risk of some cancers, such as lymphoma and lung cancer, but a lower risk of...

2011-08-10 05:11:00

MUMBAI, August 10, 2011 /PRNewswire/ -- - Revamilast is a PDE4 inhibitor, under development for Asthma, Rheumatoid Arthritis and other inflammatory disorders - The molecule successfully completed pre-clinical trials and Phase I studies - Phase I studies on healthy volunteers were carried out mainly in the UK - Glenmark has initiated global Phase IIb studies for both indications in Europe and...

2011-07-29 11:20:00

DALLAS, July 29, 2011 /PRNewswire/ -- Humira defect lawyers filed a lawsuit against Abbott Laboratories in Texas state court claiming Abbott's blockbuster drug, Humira, caused a life-threatening disease, leukemia. "Eleven year-old Bo Anderson was prescribed Humira for a skin condition, psoriasis. After taking the drug for approximately ten months, Bo's parents noticed unusual bruising covering his body while on a family vacation," says drug defect attorney Andy Vickery. "Bo...

2011-07-22 16:00:00

HORSHAM, Pa., July 22, 2011 /PRNewswire/ -- Janssen Biotech, Inc. announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response letter for its supplemental Biologics License Application (sBLA) for SIMPONI® (golimumab). The application, filed in September 2010, seeks to expand the SIMPONI® physician label to include inhibiting the progression of structural damage, inducing major clinical response (MCR) and maintenance of...

2011-07-01 08:35:02

Tokyo, July 1, 2011 - (JCN Newswire) - Abbott Japan Co., Ltd. and Eisai Co., Ltd. announced today that they have received approval from Japan's Ministry of Health, Labour, and Welfare (MHLW) for polyarticular juvenile idiopathic arthritis (JIA) as an additional indication of Humira(R) (adalimumab) Pre-filled Syringe 40 mg/0.8 mL for Subcutaneous Injection, a fully human anti-TNF-α monoclonal antibody jointly developed by the two companies in Japan.In addition to the new indication,...

2011-06-21 21:43:57

In a study that included nearly 14,000 patients with rheumatoid arthritis or psoriasis, the use of certain disease-modifying antirheumatic drugs was found to lower the risk of diabetes, according to a study in the June 22/29 issue of JAMA. Two common systemic inflammatory conditions, rheumatoid arthritis (RA) and psoriasis, predispose patients to insulin resistance and may place patients at risk for diabetes mellitus (DM). The treatment of psoriasis and RA includes disease-modifying...

2011-06-13 07:00:00

MEMPHIS, June 13, 2011 /PRNewswire/ -- Humira defect lawyers filed a lawsuit against Abbott Laboratories in federal court today claiming Abbott's blockbuster drug, Humira, caused a fungal infection resulting in the near-death of a Tennessee man. Army veteran Fred Delano was prescribed Humira in October of 2008 for psoriatic arthritis. After taking the drug for two and-a-half months, Delano was hospitalized and diagnosed with disseminated histoplasmosis, an extremely dangerous side...

2011-06-02 12:55:23

Intense distress and fear of dying, which many people experience when suffering the symptoms of a heart attack, are not only fairly common emotional responses but are also linked to biological changes that occur during the event, according to new research published online today in the European Heart Journal. These changes, in turn, are associated with other biological processes during the following weeks that can predict a worse outcome for patients. Acute coronary syndrome (ACS) is a medical...

2011-05-25 06:43:51

(Ivanhoe Newswire) "“ A powerful pro-inflammatory protein, tumor necrosis factor (TNF), can suppress aspects of inflammation. The identification of the mechanism of how this works could potentially lead to new treatment for rheumatoid arthritis. "Prior to this study, TNF has long been known as a potent pro-inflammatory cytokine, but if you look carefully through the literature, there are hints that it also has some suppressive functions, but nothing was known about the mechanisms," sid...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'