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Last updated on April 18, 2014 at 12:24 EDT

Latest Tumor suppressor genes Stories

2014-04-04 23:31:28

St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project finds TP53 gene is altered in nearly all osteosarcomas; results help explain how tumors withstand radiation therapy. Memphis, Tenn. (PRWEB) April 03, 2014 The St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project found mutations in the tumor suppressor gene TP53 in 90 percent of osteosarcomas, suggesting the alteration plays a key role early in...

2014-04-04 12:23:54

These genes could explain why some women with high-risk mutations suffer from cancer while others do not Today we know that women carrying BCRA1 and BCRA2 gene mutations have a 43% to 88% risk of developing from breast cancer before the age of 70. Taking critical decisions such as opting for preventive surgery when the risk bracket is so wide is not easy. Spanish National Cancer Research Centre (CNIO) researchers are conducting a study that will contribute towards giving every woman far...

2014-03-26 23:25:49

Fulgent Diagnostics announces a clinical BRCA1/BRCA2 full gene sequencing test for $500. Temple City, California (PRWEB) March 26, 2014 In addition to the BRCA1/BRCA2 full gene sequencing test, Fulgent Diagnostics has also added a gene rearrangement test for an additional cost of $400. Fulgent Diagnostic's BRCA1/BRCA2 full gene sequencing test with rearrangement provides valuable information that can lead to potential treatment options that could mitigate certain risks. These options...

2014-03-19 23:04:03

A study published in last month’s Journal of Clinical Oncology suggests that women with the BRCA1 gene mutation may significantly reduce their chances of ovarian cancer if they have their ovaries removed by age 35. Abington, PA (PRWEB) March 19, 2014 Among study participants who underwent oophorectomy (ovary removal surgery), their chances of ovarian and breast cancers decreased by 80 percent. Additionally, their risk of death from any cause by age 70 decreased 77 percent as a result of...

2014-03-12 11:43:12

The gene known to be associated with breast cancer susceptibility, BRCA 1, plays a critical role in the normal metabolic function of skeletal muscle, according to a new study led by University of Maryland School of Public Health researchers. Dr. Espen Spangenburg, associate professor of kinesiology, and his laboratory team are the first to identify that the BRCA1 protein is expressed in the skeletal muscle of both mice and humans, and that it plays a key role in fat storage, insulin response...

2014-02-27 16:26:09

COMBINING SCIENCE AND ART, THE SCULPTURE ECHOES THE OPTIMISM SURROUNDING RECENT BREAKTHROUGHS IN BREAST CANCER RESEARCH NEW YORK, Feb. 27, 2014 /PRNewswire/ -- On March 12, 2014, the Basser Research Center for BRCA, at the Ruth and Raymond Perelman Center for Advanced Medicine in Philadelphia, Pennsylvania, will unveil "Homologous Hope," a dramatic sculpture commissioned from internationally renowned artist Mara G. Haseltine. http://photos.prnewswire.com/prnvar/20140227/NY73843 An...

Protein Study Opens A New Avenue For Cancer Researchers
2014-02-04 13:09:26

Brigham Young University One of the hopes for victory against cancer hinges on naturally-occurring proteins whose job is to make their host cell die. Since their natural role is to stop unhealthy cell proliferation, the idea is that one or more of these proteins could be harnessed to stop the growth of tumors. Brigham Young University scientists recently stumbled onto one potential tumor suppressor with an especially ominous name: Programmed Cell Death Protein 5 (aka PDCD5). What...

2014-01-24 13:26:27

In laboratory experiments conducted on human cell lines at the Johns Hopkins Kimmel Cancer Center, scientists have shown that people carrying certain mutations in two hereditary cancer genes, BRCA2 and PALB2, may have a higher than usual susceptibility to DNA damage caused by a byproduct of alcohol, called acetaldehyde. The scientists say they suspect that the two genes in their normal forms evolved to protect cells against the damaging effects of acetaldehyde, which can lead to cancer....

2014-01-22 12:11:01

Genetic counseling delivered over the telephone is as effective as face-to-face counseling, finds the largest randomized study to date comparing the two methods. The multi-center study, led by researchers at Georgetown Lombardi Comprehensive Cancer Center, was reported today in the Journal of Clinical Oncology. The landscape of genetic testing has broadened to include a range of diseases, and demand for testing and counseling has greatly increased because of direct-to-consumer marketing,...

2014-01-11 23:01:48

The US Supreme court ruled recently that the test patent is no longer valid causing pricing for Genetic testing to plummet. Thousand Oaks, CA (PRWEB) January 11, 2014 BRCA gene is currently the most well known breast cancer (and ovarian cancer) gene. Women with a BRCA1 and/or BRCA2 gene mutation are up to eight times more likely to develop breast malignancy than women without. In other words, the lifetime risk for getting breast cancer is up to 85%. If and when cancer happens, it tends...