Latest Tumor suppressor genes Stories
A molecule widely believed to fight many forms of cancer actually helps deadly thyroid tumors grow, and cancer therapies now being tested in humans might boost the activity of this newly revealed bad guy.
Presence of normal p53, a tumor suppressor gene, instead of a mutated version, makes breast cancer chemotherapy with doxorubicin less effective.
A new study describes a compound that selectively kills cancer cells by restoring the structure and function of one of the most commonly mutated proteins in human cancer, the "tumor suppressor" p53.
Melanoma – the deadliest and most aggressive form of skin cancer – has long been linked to time spent in the sun.
When collaborators led by those at Baylor College of Medicine and Stanford University School of Medicine sought to unravel the mysterious role of the enzyme SIRT7 in the cell, they discovered a saboteur that uses other molecules to maintain tumor cells in their cancer state, suppressing the systems that are supposed to prevent that malignant transformation.
Scientists at Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan-Kettering Cancer Center have amassed strong experimental evidence implying that commonly occurring large chromosomal deletions that are seen in many cancer types contain areas harboring multiple functionally linked genes whose loss, they posit, confers a survival advantage on growing tumors.
Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL).
An international team of scientists has announced a new advance in the ability to target and destroy certain cancer cells.