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Latest Tumor suppressor genes Stories

Genetic Variation Fuels Testicular Cancer
2013-10-11 04:33:32

Brett Smith for redOrbit.com - Your Universe Online Using a genomic analysis, a team of international researchers has identified a specific mutation responsible for a dramatic increase in the risk for testicular cancer. The mutation is a single-base change to the genetic code that affects the activity of the p53 protein that is responsible for regulating the activity of a large number of genes, including those responsible for protection from UV rays – according to the team’s report...

2013-10-08 13:53:37

Technology as sensitive as standard methodology but more efficient, say researchers in the Journal of Molecular Diagnostics The recognition of a causal link between mutations in BRCA1 and BRCA2 genes and increased risk of developing breast and ovarian cancer has intensified the demand for genetic testing. Identifying mutations in these large genes by conventional methods can be time consuming and costly. A report in the November issue of the Journal of Molecular Diagnostics describes a new...

2013-10-08 13:26:58

A study led by Marcos Malumbres, head of CNIO's Cell Division & Cancer Group, identifies a new molecular mechanism that regulates genome stability and cell proliferation Cell division is an essential process for the development of an organism. This process, however, can cause tumor growth when it stops working properly. Tumor cells accumulate alterations in their genetic material, and this makes them divide in an uncontrolled fashion, thus encouraging growth of the tumor. Over the past...

2013-09-09 11:33:35

For the first time, a genetic link specific to risk of childhood leukemia has been identified, according to a team of researchers from Memorial Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, University of Washington, and other institutions. The discovery was reported online today in the journal Nature Genetics. "We're in unchartered territory," said study author Kenneth Offit, MD, MPH, Chief of the Clinical Genetics Service at Memorial Sloan-Kettering. "At the very...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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