Latest Tumor suppressor genes Stories
For the first time, a genetic link specific to risk of childhood leukemia has been identified.
A person’s hair color and skin tone is determined by their skin pigment. This pigment is influenced by the melanocortin-1 (MC1R) gene receptor. For the world’s redheads – one to two percent of the population – their coloration is accounted for by a mutation in MC1R.
The global study was led by University of Melbourne and the Peter MacCallum Cancer Centre and published in the Journal of Clinical Oncology today.
Scientists at the Princess Margaret Cancer Centre have discovered a function of the tumor suppressor gene PTEN that helps explain why certain promising therapies fail in many cancer patients, a finding that could aid in delivering tailored, personalized cancer medicine based on an individual's genetics.
Genetic mutations aren’t the only thing that can keep a protein called PTEN from doing its tumor-suppressing job.
It is estimated that between 5% and 10% of breast and ovarian cancers are familial in origin, which is to say that these tumors are attributable to inherited mutations from the parents in genes such as BRCA1 or BRCA2.
- a slit in a tire to drain away surface water and improve traction.