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Latest Tumor suppressor genes Stories

2013-05-20 23:04:32

Angelina Jolie´s recent news of opting to have a double mastectomy because she has the BRCA1 gene mutation shows how pertinent organizations such as Bright Pink® are to educating women about their choices for optimum health. Chicago (PRWEB) May 20, 2013 The American Society for Clinical Pathology (ASCP) set out to raise $5,000 for Bright Pink®, the organization that empowers young women to be proactive with their breast and ovarian health, by the end of 2012. Thanks to its...

2013-05-19 23:01:26

Australian Researchers Astonished to Learn P53 Not Only Seeks and Destroys, But Prevents DALLAS (PRWEB) May 19, 2013 Scientists are on the verge of unraveling the genesis of cancer. By studying the behavior of distorted genes in the malignant microenvironment (inside the body) studies are attempting to recode damaged gene signals so the body´s immune system can search and destroy cancer. But that´s not all. 1 P53 protein has long been the subject of intense investigation because...

2013-05-16 23:25:31

Jean LaMantia, Registered Dietitian, Cancer Survivor and Author of The Essential Cancer Treatment Nutrition Guide and Cookbook, advises that women with and without the BRCA1 and BRCA2 gene mutations can all take preventative measures. Toronto, ON (PRWEB) May 16, 2013 While some women like Angelina Jolie are aware of their susceptibility to breast cancer and take action to prevent it, not all have the benefit of genetic testing that can forecast looming health risks. Breast cancer caused by...

2013-05-09 23:04:11

A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing them to fend off stress, says a University of Colorado Boulder study. Boulder, CO (PRWEB) May 09, 2013 A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing...

2013-05-06 20:49:32

Researchers at the Stanford University School of Medicine have identified a group of proteins that are mutated in about one-fifth of all human cancers. The finding suggests that the proteins, which are members of a protein complex that affects how DNA is packaged in cells, work to suppress the development of tumors in many types of tissues. The broad reach of the effect of mutations in the complex, called BAF, rivals that of another well-known tumor suppressor called p53. It also furthers...

2013-04-25 20:23:59

New research reveals how the tumor suppressor p53 is shut down in metastatic melanoma -- and how it can be revived Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond...

2013-04-23 12:06:30

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment.  They suggest that this is because p53 regulates the expression of two enzymes (JMJD2b and SUV39H1) that control the folding of DNA. According to the researchers, p53 is highly inducible by radiation. Activation of p53 stabilizes chromosomes by promoting the repair of heterochromatin DNA, which controls the expression of...

2013-04-18 23:31:32

This study will improve genetic counseling and clinical monitoring of patients and families who present these variants Researchers of the hereditary cancer research group at the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO) conducted a functional and structural study of seven missense variants of the BRCA1 gene concluding that three of these variants are pathogenic, linked to the risk of suffering breast or ovarian cancer. The study has been...

Patent Law For The Human Genome
2013-04-15 06:01:44

redOrbit Staff & Wire Reports - Your Universe Online The US Supreme Court will hear oral arguments on Monday in a case that could determine whether or not human DNA can be patented, which could have a tremendous impact on genetic research, one way or the other. According to Reuters reporter Sharon Begley, “The US Patent and Trademark Office has granted patents on at least 4,000 human genes to companies, universities and others that have discovered and decoded them.”...

2013-04-02 12:32:57

Mutations in a protein called SPOP (speckle-type POZ protein) disarm it, allowing another protein called steroid receptor coactivator-3 (SRC-3) to encourage the proliferation and spread of prostate cancer cells, said researchers led by those at Baylor College of Medicine in a report that appears online in Proceedings of the National Academy of Sciences. Normally SPOP acts as a tumor suppressor gene by marking SRC-3 for destruction, said Dr. Nicholas Mitsiades, assistant professor of...


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