Quantcast

Latest Tumor suppressor genes Stories

2012-12-11 21:46:12

Mice without the pro-longevity gene SIRT6 had higher risk of gastrointestinal cancers A new study sheds more light on how an anti-aging gene suppresses cancer growth, joint University of Michigan Health System and Harvard Medical School research shows. Loss of the SIRT6 protein in mice increases the number, size and aggressiveness of tumors, according to the new research published in the scientific journal Cell. The study also suggests that the loss of SIRT6 promotes tumor growth in...

2012-12-03 13:47:06

Researchers from the University of Geneva demonstrate that, in this type of lesion, the rate of progression from a precancerous state to the tumor stage accelerates over time The causes underlying the development of certain types of common cancers have not yet been elucidated. In order to better determine the origin and the sequence of events responsible for the onset of colon cancer, the teams led by Thanos Halazonetis and Stylianos Antonarakis, professors at the University of Geneva...

2012-11-29 14:32:03

The combined loss of two tumor suppressor genes, retinoblastoma (RB) and phosphatase and tensin homolog (PTEN) was shown to be strongly associated with progression of DCIS to invasive breast cancer, according to a study published November 28 in the Journal of the National Cancer Institute. Ductal carcinoma in situ (DCIS) is a breast cancer precursor lesion for which there are no established markers defining risk of progression to invasive breast cancer. As a result, the majority of...

2012-11-15 12:37:11

An animal study conducted by researchers at Georgetown Lombardi Comprehensive Cancer Center raises questions about the consequences of diet – specifically glucose, the plant-based sugar that fuels cell life – on increased activity of an oncogene that drives tumor growth. In the study published online today in the journal Cell Cycle, the scientists report, for the first time, that high levels of glucose in the diet of mice with cancer is linked to increased expression of mutant...

Cold Viruses Could Help Find New Cancer Therapies
2012-10-17 11:03:01

[ Watch The Video ] Salk findings on cold virus proteins may spur new cancer treatments Cold viruses generally get a bad rap----which they've certainly earned----but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ally in the fight against cancer. Adenovirus, a type of cold virus, has developed molecular tools----proteins----that allow it to hijack a cell's molecular machinery, including large...

2012-09-20 11:23:52

Decorin, a well-studied protein, induces tumor suppressor genes in microenvironment to stop metastasis, Thomas Jefferson University researchers say A natural substance found in the surrounding tissue of a tumor may be a promising weapon to stop triple negative breast cancer from metastasizing. A preclinical study published in PLOS ONE September 19 by Thomas Jefferson University researchers found that decorin, a well-studied protein known to help halt tumor growth, induces a series of...

2012-08-13 11:10:54

Scientists affiliated with the UC Davis MIND Institute have discovered how a defective gene causes brain changes that lead to the atypical social behavior characteristic of autism. The research offers a potential target for drugs to treat the condition. Earlier research already has shown that the gene is defective in children with autism, but its effect on neurons in the brain was not known. The new studies in mice show that abnormal action of just this one gene disrupted energy use in...

2012-07-10 10:48:44

Cylene and Peter Mac findings establish activation of p53 by targeting Pol I with CX-5461 selectively kills cancer Cylene Pharmaceuticals today announced that research collaborators at the Peter MacCallum Cancer Centre (Peter Mac) in Melbourne, Australia have established, for the first time, that RNA Polymerase I (Pol I) activity is essential for cancer cell survival and that its inhibition selectively activates p53 to kill tumors. Published today in Cancer Cell, the findings show that...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
Related