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2013-12-06 11:25:58

Findings could reshape research on cancer origins and treatment of other autoimmune diseases Johns Hopkins scientists have found evidence that cancer triggers the autoimmune disease scleroderma, which causes thickening and hardening of the skin and widespread organ damage. A report on the discovery, published in the Dec. 5 issue of Science, also suggests that a normal immune system is critical for preventing the development of common types of cancer. According to researchers,...

2013-12-06 11:11:38

Tumor cells temporarily lose mutation to evade drugs targeting mutation A team of scientists, led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine, has found that brain cancer cells resist therapy by dialing down the gene mutation targeted by drugs, then re-amplify that growth-promoting mutation after therapy has stopped. The...

2013-12-06 11:09:42

Researchers at the University of Geneva, Switzerland, discover how tumor cells solve the problems linked to the replication of their unstable DNA Genomes must be replicated in two copies during cell division. This process occurs at structures called 'replication forks', which are equipped with enzymes and move along the separated DNA strands. In tumor cells, the replication forks are frequently damaged, giving rise to breaks in the double-stranded DNA. An international study led by Thanos...

2013-12-03 23:27:34

TG02 synergizes with carfilzomib in multiple myeloma models; data to be presented at ASH 2013 Annual Meeting. San Diego (PRWEB) December 03, 2013 Tragara Pharmaceuticals, Inc. today announced the initiation of a phase 1b clinical trial of TG02, in combination with the poteosome inhibitor carfilzomib (Kyprolis®), in patients with relapsed or refractory multiple myeloma. TG02 is a potent oral inhibitor of CDK9, which leads to the depletion of key survival proteins, such as Mcl-1,...

Breast Cancer Risk From High Cholesterol
2013-11-30 04:57:15

Rebekah Eliason for redOrbit.com - Your Universe Online Researchers have discovered a byproduct of cholesterol that functions similarly to the hormone estrogen and stimulates the growth and spread of common forms of breast cancer cells. Encouragingly, researchers also found that certain anti-cholesterol drugs, like statins, seem to reduce the harmful effects of the estrogen-like molecule. The researchers caution, however, that the study's findings are still early in their development....


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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