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Latest Tumors Stories

2012-12-07 12:45:39

Unprecedented genomic sequencing of 14 metastatic TNBC patients yields potential drug targets Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) and US Oncology Research. The study is published by the journal Molecular Cancer Therapeutics and is currently available online. By sequencing, or spelling out, the billions...

2012-11-27 13:06:13

PKM2 slips into nucleus to promote cancer; potential biomarker and drug approach discovered Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which brain tumors thrive. They also found a vital spot along the protein's journey that can be attacked with a type of drug not yet deployed against glioblastoma multiforme, the...

2012-11-26 11:21:26

-People with a type of brain tumor called glioblastoma live 12 months on average, so new forms of treatment for this malignancy are badly needed. -Viruses designed to kill cancer cells offer a safe way to treat these tumors, but the therapy doesn't work as well as expected. -This study found that a patient's immune system tries to eliminate the anticancer virus and blocking this immune activity gave the virus more time to kill cancer cells. Doctors now use cancer-killing viruses to treat...

2012-11-15 12:37:11

An animal study conducted by researchers at Georgetown Lombardi Comprehensive Cancer Center raises questions about the consequences of diet – specifically glucose, the plant-based sugar that fuels cell life – on increased activity of an oncogene that drives tumor growth. In the study published online today in the journal Cell Cycle, the scientists report, for the first time, that high levels of glucose in the diet of mice with cancer is linked to increased expression of mutant...

2012-11-14 12:59:15

Affected pathway also involved in autism, Alzheimer's, Parkinson's A drug originally developed to prevent the rejection of transplanted organs has now been shown to dramatically reduce a particular kind of brain tumor in patients with tuberous sclerosis complex (TSC) -- a genetic disease that causes tumors to grow on vital organs. The study, published online in The Lancet, is the latest to show the effectiveness of everolimus in slowing the cell growth that is overactive in patients...

2012-10-24 23:54:10

Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers–or antigens–on cancer cells and destroy them before they grow into tumors. Cancer cells, for their part, evolve constantly to evade such assassination. Those that succeed become full-blown malignancies. Yet, given the right sort of help, the immune system can destroy even these entrenched tumors. In the October 22nd issue...

New Discovery May Help Doctors Slow Progression And Recurrence Of Brain Cancer
2012-10-22 20:57:41

Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science Express, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons. GBM is one of the most devastating...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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