Latest Tumors Stories
Joslin study uncovers potential targets for treating disease Scientists at Joslin Diabetes Center in Boston have uncovered important molecular and genetic keys to the development of soft-tissue sarcomas in skeletal muscle, giving researchers and clinicians additional targets to stop the growth of these often deadly tumors. Published in the Proceedings of the National Academy of Sciences, the study identified two major molecular signaling pathways (the Ras and mTOR pathways) that are...
IRVING, Texas, Nov. 29, 2011 /PRNewswire/ -- A new study in The Journal of Clinical Investigation (JCI) has uncovered a novel mechanism that cancer cells may use to escape detection by the body's immune system. The study, "Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice," led by researchers at the H. Lee Moffitt Cancer Center in Tampa, Fla., shows that a specific type of immature white blood cells (myeloid derived suppressor cells or...
(Ivanhoe Newswire) – Hope for new and better cancer treatment! According to a recent study, researchers were able to shrink tumors and minimize side effects using tumor-homing peptide to deliver treatment. Scientists show that coupling a tumor-homing peptide and an anti-cancer drug drastically reduces tumors in a mouse model of colon cancer, with no apparent side effects; the technique could be applied to many types of cancer. "We can cure terminal stage mice with very large tumors...
Finding could lead to new cancer-stopping therapies A research team led by UT Southwestern Medical Center scientists has identified an atypical metabolic pathway unique to some tumors, possibly providing a future target for drugs that could reduce or halt the spread of cancer. Dr. Ralph DeBerardinis, senior author of the study published Nov. 20 in Nature, likened the newly discovered pathway to traffic that is rerouted during a highway construction project. "If we hone in on this...
Hydrogen peroxide isn't just that bottled colorless liquid in the back of the medicine cabinet that's used occasionally for cleaning scraped knees and cut fingers. It's also a natural chemical in the body that rallies at wound sites, jump-starting immune cells into a series of events. A burst of hydrogen peroxide causes neutrophils, the immune system's first responders, to rush to the wound to fight microorganisms, remove damaged tissue and then start the inflammation process....
Tumors can grow for 10 years or longer before currently available blood tests will detect them, a new mathematical model developed by Stanford University School of Medicine scientists indicates. The analysis, which was restricted to ovarian tumors but is broadly applicable across all solid tumor types, will be published online Nov. 16 in Science Translational Medicine. "The study's results can be viewed as both bad and good news," said Sanjiv "Sam" Gambhir, MD, PhD, professor and chair of...
UCSF researchers discuss possible multi-drug strategy for breast cancer at news conference In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because they develop resistance to it over time. Now researchers at the University of California, San Francisco (UCSF) have discovered the molecular basis for tamoxifen resistance and...
UC San Diego researchers find surprising role for enzyme in tumor cell division and new drug to combat it Researchers at the University of California, San Diego School of Medicine and the UC San Diego Moores Cancer Center have identified a new drug discovery approach enabling the destruction of the most highly proliferative tumors. The discovery, published in the Nov. 13 online issue of the journal Nature Medicine, points to an effective, alternative method for killing fast-growing cancer...
SAN FRANCISCO, Nov. 2, 2011 /PRNewswire/ -- Jennerex, Inc., a private clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic products for cancer, today announced that final data from its Phase 2 randomized clinical trial in advanced liver cancer patients will be presented on Monday, November 7, 2011 at the 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) taking place November 4-8,...
New discoveries about follicular lymphoma, a currently intractable form of cancer, highlight the power of functional genomics in cancer gene discovery. A report in the Oct 28th issue of Cell, a Cell Press publication, demonstrates how genetic insights can be translated directly into therapies. The findings are but one example of what has now become possible given the avalanche of data on cancer genomes. "With access to tumor genomic data, suddenly we can do this; we know what has...
