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Latest Type three secretion system Stories

Work On Microbial Signaling Offers A Window Into Better Biofuels, Human Health
2014-04-25 03:28:23

Tom Rickey, DOE/Pacific Northwest National Laboratory A common plant puts out a welcome mat to bacteria seeking to invade, and scientists have discovered the mat's molecular mix. The study published this week in the Proceedings of the National Academy of Sciences reveals new targets during the battle between microbe and host that researchers can exploit to protect plants. The team showed that the humble and oft-studied plant Arabidopsis puts out a molecular signal that invites an...

2013-12-12 11:01:55

Scientists have used a new method to map the response of every salmonella gene to conditions in the human body, providing new insight into how the bacteria triggers infection. In a world first, the scientists exposed salmonella to 22 lab environments that mimic conditions that the bacterium finds when it enters the human body and discovered the effects of these conditions on individual genes in the bacteria. After people eat salmonella, the microbes enter the stomach, and intestine, and...

2013-05-28 11:30:47

Possibly energy-conserving, switch suggests metabolic changes that researchers might exploit to fight systemic illness For the first time, researchers have found a particular kind of molecular switch in the food poisoning bacteria Salmonella Typhimurium under infection-like conditions. This switch, using a process called S-thiolation, appears to be used by the bacteria to respond to changes in the environment during infection and might protect it from harm, researchers report this week...

How Does Salmonella Spread Through The Body?
2012-12-08 07:36:40

redOrbit Staff & Wire Reports - Your Universe Online A study from Cambridge University researchers shines new light on exactly how Salmonella spreads throughout a person's body -- work that could help medical experts overcome roadblocks in the development of vaccines and other forms of therapy to help combat the disease-causing bacteria. By analyzing salmonellae, which are typically found growing inside of immune system cells during an infection, the researchers discovered the...

2012-05-22 00:43:48

Max Planck scientists decipher the structure of bacterial injection needles at atomic resolution The plague, bacterial dysentery, and cholera have one thing in common: These dangerous diseases are caused by bacteria which infect their host using a sophisticated injection apparatus. Through needle-like structures, they release molecular agents into their host cell, thereby evading the immune response. Researchers at the Max Planck Institute for Biophysical Chemistry in...

Some Bacteria Attack Using Poison Daggers
2012-02-27 10:00:41

[ Watch the Video ] Bacteria have evolved different systems for secreting proteins into the fluid around them or into other cells. Some, for example, have syringe-like exterior structures that can pierce other cells and inject proteins. Another system, called a type VI secretion system, is found in about a quarter of all bacteria with two membranes. Despite being common, researchers have not understood how it works. Now a team, co-led by researchers at the California Institute of...

2012-02-10 11:37:39

Scientists from Queen Mary, University of London have discovered the workings behind some of the bacteria that kill hundreds of thousands every year, possibly paving the way for new antibiotics that could treat infections more effectively. With antibiotic resistance on the rise in strains of pathogenic bacteria, innovative strategies are needed to discover ways of treating bacterial infections in both humans and in agriculture. Writing in the journal PLoS Pathogens, the team from Queen...

2012-01-06 09:46:45

Understanding the structure of the TAL effector may be key for targeted gene correction Researchers at Fred Hutchinson Cancer Research Center have solved the three-dimensional structure of a newly discovered type of gene-targeting protein that has shown to be useful as a DNA-targeting molecule for gene correction, gene therapy and gene modification. The findings are published online in Science Express on Jan. 5. Using a unique form of computational and X-ray crystallographic analyses, a...

2011-05-10 16:08:35

Study by UAB researchers published in PLoS ONE Salmonella enterica, one of the main causes of gastrointestinal infections, modulates its virulence gene expression, adapting it to each stage of the infection process, depending on the free iron concentration found in the intestinal epithelium of its host. Researchers at Universitat Autònoma de Barcelona (UAB) have demonstrated for the first time that the pathogen activates these genes through the Fur protein, which acts as a...

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2011-02-04 08:24:14

The potentially deadly bacterium Salmonella possesses a molecular machine that marshals the proteins it needs to hijack cellular mechanisms and infect millions worldwide. In a paper published Feb. 3 online in Science Express, Yale University researchers describe in detail how Salmonella, a major cause of food poisoning and typhoid fever, is able to make these proteins line in up in just the right sequence to invade host cells. "These mechanisms present us with novel targets that might form...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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